Kidney Transplant

Positive Crossmatch Kidney Transplant

Since January 2000, the Mayo Clinic Kidney Transplant Program has had an active protocol for kidney transplantation in patients who have developed antibodies against their kidney donor (positive crossmatch). These antibodies usually occur after pregnancy, blood transfusion, or a previous kidney transplant. Historically, a positive crossmatch was thought to make transplantation impossible.

Mayo Clinic's protocol allows transplant surgeons to successfully perform a kidney transplant despite the presence of these potentially harmful antibodies, with a success rate similar to that seen in cadaveric kidney transplants.

Positive crossmatch kidney transplant is offered Mayo Clinic in Rochester and Mayo Clinic in Scottsdale. Mayo Clinic in Jacksonville offers flow crossmatch transplant in some patients.