Mayo Clinic in Arizona opened its doors as a premier academic medical center in the southwestern United States in 1987. Today, it provides specialty and surgical care in more than 66 disciplines, including programs in cancer and organ transplantation.

The integrated, multicampus system consists of an outpatient facility in north Scottsdale, Mayo Clinic Hospital in northeast Phoenix, and several primary care centers located throughout the metropolitan Phoenix area.

In Scottsdale, Mayo Clinic is located on 284 acres of the Sonoran desert in the foothills of the McDowell Mountains. In addition to the clinic building, the Scottsdale campus has a medical research center, several administrative buildings and a scenic nature trail.

Mayo Clinic Hospital opened in northeast Phoenix in 1998 and is the first hospital designed and built by Mayo Clinic. The hospital supports patients seen in all of the outpatient clinic's medical and surgical specialty programs, including organ transplantation, and has a Level II emergency department. An adjoining facility on the Phoenix campus offers outpatient specialty services.