Although the specific causes of hypertrophic cardiomyopathy are not yet fully known, the primary cause seems to be genetic. Nongenetic causes may also influence who will develop this disease.
Research has shown that about 50 percent of patients with hypertrophic cardiomyopathy have a close relative who also has the condition. Other nongenetic influences may play a part in determining who will develop hypertrophic cardiomyopathy. The condition appears to occur equally in men and women.