Hyperoxaluria and Oxalosis

Symptoms

The first sign of hyperoxaluria is most typically a kidney stone. Symptoms of a kidney stone can include:

• Severe or sudden abdominal pain
• Blood in the urine
• Urge to urinate often
• Pain when urinating
• Fever and chills
• Urinary tract infection

Since kidney stones are uncommon in childhood, all children and adolescents who have symptoms of kidney stones or are diagnosed with kidney stones should be screened for hyperoxaluria. Children with more severe hyperoxaluria can then be screened for primary hyperoxaluria via more specialized testing.

If primary hyperoxaluria goes untreated, the kidneys will eventually be damaged and may stop working. Signs of kidney failure include:

• A decrease in or no urine output
• General ill feeling, tiredness and fatigue
• Nausea, vomiting

Oxalosis in its late stages will cause a variety of complications outside the kidney, including bone disease, anemia, skin ulcers, and heart and eye problems.