Hyperoxaluria and Oxalosis

Overview

Mayo Clinic provides medical care for children and adults with all degrees and stages of hyperoxaluria and oxalosis, from comprehensive assessment and diagnosis to a full range of treatment options, including organ transplantation for patients whose kidneys have quit functioning as a result of hyperoxaluria.

Mayo Clinic in Rochester is one of the most experienced centers in the world in treating patients with hyperoxaluria and oxalosis. The Hyperoxaluria Center in Rochester coordinates the care of both children and adults with this condition and conducts research.

Diagnosis

Mayo Clinic offers tests to help diagnose hyperoxaluria and oxalosis in those with symptoms. Tests are tailored to each patient's needs. They may include urine and blood testing, measurements of kidney function, radiographic studies (such as ultrasound, CT scanning, or X-ray), liver biopsy, and family genetic screening. Echocardiograms of the heart and eye and bone marrow examinations may be recommended. Read more about hyperoxaluria and oxalosis diagnosis.

Treatment Options

Mayo's treatment approach depends on each person's needs, considering the type and severity of disease and how well the patient responds to treatment. Treatment options include medications, fluid and dietary modifications and, in severe cases, dialysis and kidney and liver transplantation. Patients also have access to experimental treatments. Read more about hyperoxaluria and oxalosis treatment options.

• Treatment in Arizona
• Treatment in Florida
• Treatment in Minnesota
• Treatment of Children & Adolescents

What is Hyperoxaluria and Oxalosis?

Hyperoxaluria is a condition where too much of a substance called oxalate is present in the urine. Mild forms of hyperoxaluria are relatively common and can cause kidney stones. Larger amounts of oxalate in the urine can be caused by over-absoption of oxalate due to intestinal diseases. Primary hyperoxaluria is a rare genetic (inherited) disorder that is present at birth. Primary hyperoxaluria causes severe hyperoxaluria, and many patients begin to form kidney stones in childhood. Read more about hyperoxaluria and oxalosis.