Overview

Churg-Strauss syndrome is a disorder marked by blood vessel inflammation. This inflammation can restrict blood flow to vital organs and tissues, sometimes permanently damaging them. This condition is also known as eosinophilic granulomatosis (gran-u-low-muh-TOE-sis) with polyangiitis (pol-e-an-jee-I-tis).

Asthma is the most common sign of Churg-Strauss syndrome. The disorder can also cause a variety of other problems, such as hay fever, rash, gastrointestinal bleeding, and pain and numbness in your hands and feet.

Churg-Strauss syndrome is rare and has no cure. But your doctor can usually help you control symptoms with steroids and other powerful immunosuppressant drugs.

Aug. 16, 2016
References
  1. Greco A, et al. Churg-Strauss syndrome. Autoimmunity Reviews. 2015;14:341.
  2. Churg Strauss syndrome. National Organization for Rare Disorders. http://rarediseases.org/rare-diseases/churg-strauss-syndrome/. Accessed June 25, 2016.
  3. Churg-Strauss syndrome (CSS). American Academy of Allergy, Asthma and Immunology. http://www.aaaai.org/conditions-and-treatments/related-conditions/churg-strauss-syndrome. Accessed June 25, 2016.
  4. King TE. Clinical features and diagnosis of eosinophilic granulomatosis with polyangiitis (ChurgStrauss). http://www.uptodate.com/home. Accessed June 25, 2016.
  5. Ferri FF. Eosinophilic granulomatosis with polyangiitis (ChurgStrauss syndrome). In: Ferri's Clinical Advisor 2016. Philadelphia, Pa.: Mosby Elsevier; 2016. https://www.clinicalkey.com. Accessed June 25, 2016.
  6. Masi AT, et al. The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). Arthritis and Rheumatism. 1990;33:1094.
  7. Medication and side effects. The Churg-Strauss Syndrome Association. http://www.cssassociation.org/medications-and-side-effects.html. Accessed June 27, 2016.
  8. Eosinophilic granulomatosis with polyangiitis (EGPA/ChurgStrauss syndrome). Vasculitis Foundation. http://www.vasculitisfoundation.org/education/forms/eosinophilic-granulomatosis-with-polyangiitis-churg-strauss-syndrome/. Accessed June 25, 2016.