Studies of hospitalized patients — who often have lower than normal vitamin C levels — have found that they experienced an improvement in mood after they received vitamin C.
The link between vitamin C and mood may seem surprising, but it's not so far-fetched. People who have vitamin C deficiency often feel fatigued or depressed. Plus, some studies show that vitamin C can have mood-elevating effects. So it makes sense that vitamin C levels could affect mood — but more research is needed.
In the meantime, eat plenty of fruits and vegetables rich in vitamin C. If you also take a supplement, try not to exceed the upper limit of 2,000 milligrams of vitamin C a day. As always, talk to your doctor first before taking any supplement.
Oct. 10, 2014
- Vitamin C ascorbic acid. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed July 25, 2014.
- Zhang M, et al. Vitamin C provision improves mood in acutely hospitalized patients. Nutrition. 2011;27:530.
- Lykkesfeld J, et al. Is vitamin C supplementation beneficial? Lessons learned from randomized controlled trials. British Journal of Nutrition. 2010;103:1251.
- Binfare RW, et al. Ascorbic acid administration produces an antidepressant-like effect: Evidence for the involvement of monoaminergic neurotransmission. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2009;33:530.
- Wang Y, et al. Effects of vitamin C and vitamin D administration on mood and distress in acutely hospitalized patients. American Journal of Clinical Nutrition. 2013;98:705.
- Bauer BA (expert opinion). Mayo Clinic, Rochester, Minn. July 25, 2014.
- Gautam M, et al. Role of antioxidants in generalised anxiety disorder and depression. Indian Journal of Psychiatry. 2012;54:244.
- Brody S. High-dose ascorbic acid increases intercourse frequency and improves mood: A randomized controlled clinical trial. Biological Psychiatry. 2002;52:371.