Gastroesophageal Reflux Disease (GERD)

Clinical Trials

Below is a list of Gastroesophageal Reflux Disease (GERD) clinical trials from the clinical trials database at Mayo Clinic.

This list includes only trials about which Mayo researchers choose to publish information. Mayo Clinic may be conducting other trials which are not in this database. Mayo's clinical trials include experimental treatments, often unavailable elsewhere, which frequently lead to improved patient care for people worldwide. Patients should ask their doctor at Mayo about clinical trials appropriate for their situation.

LINX Reflux Management Study
In patients with gastroesophageal reflux disease, the natural barrier has lost the muscular tone necessary to keep the contents of the stomach from routinely "refluxing" into the esophagus.

This reflux is responsible for the discomfort of heartburn. More importantly, it can damage the walls of the esophagus and lead to more serious conditions such as esophagitis and Barrett's esophagus.

The LINX System is an investigational device designed to restore the function of the lower esophageal sphincter; preventing reflux and many of the symptoms that accompany it.

The LINX device is made of titanium beads that are linked together to take the shape of a small bracelet. Each of these beads contains a magnetic core that attracts it to the beads next to it.

Using a surgical technique called laparoscopy, the device is placed around the esophagus in the area of the lower esophageal sphincter. Once in place, the magnetic attraction between the beads may help support the esophagus to prevent reflux.
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