Gastric Cancer

Research

Mayo Clinic researchers have published more original gastroenterology research articles than any other institution in the world. Currently the National Institutes of Health provides funding for more than three dozen research grants at Mayo.

Cancer research is multifaceted and often interrelated. Laboratory-based research is the study of cancer cells and the biological mechanisms within those cells to better understand the origin and growth of cancer. Translational research involves researchers and clinicians determining how laboratory results may be applied to benefit people with cancer diagnostically and therapeutically. Population science examines large groups of individuals to find patterns within specific cancers and thereby gain greater understanding to prevent, detect and control them.

Mayo Clinic Cancer Center is actively involved in all of those areas of research. The Cancer Center's experienced scientists, physicians and clinical researchers work in all aspects of cancer investigation. The resulting synergy leads to new, improved ways to care for people with cancer.

For more information about Mayo Clinic research, visit the Division of Gastroenterology & Hepatology Research Web page.

Publications

Ajani JA, Mansfield PF, Janjan N, Morris J, Pisters P, Lynch P, Feig B, Myerson R, Nivers R, Cohen D, Gunderson LL. A multi-institutional trial of preoperative chemoradiotherapy in patients with potentially resectable gastric cancer. J Clin Oncol, 22:2274-2780, 2004. [Abstract]

Calvo FC, Martinez-Marge R, Ortiz de Urbina D, Gunderson LL. Gastric Cancer. Chapter in Gunderson, L.L., Tepper, J. (Editors). Clinical Radiation Oncology. Churchill Livingstone. pp:652-685, 2000.

Fuchs C, Fitzgerald TJ, Mamon H, Haller D, Venook A, Enzinger P, Goldberg R, Gunderson L, Mayer R, Tepper J. Postoperative adjuvant chemoradiation for gastric or gastroesophageal adenocarcinoma using epirubicin, cisplatin and infusional (CI) 5-fluorouracil (ECF) before and after 5-FU and radiotherapy (RT): A multicenter pilot study. ASCO abstract # 1029. J Clin Oncol 22:257, 2003.

Gunderson LL. Gastric cancer - patterns of relapse after surgical resection. In Gastric Cancer (Ed) J Tepper. Seminars in Rad Oncol 12:150-161, 2002.

Gunderson LL, Donohue J, Alberts S. Gastric Cancer. In Clinical Oncology, 3rd Edition (Ed) Abeloff MD, Armitage JO, Lichter AS, Niederhuber JE. Churchill Livingstone, New York, pp 1819-1862, 2004.

Gunderson LL, Donohue J, Burch PA. Gastric Cancer. Chapter 60 in Clinical Oncology Edition Two. (Ed) Abeloff MD, Armitage JO, Lichter AS, Niederhuber JE. Churchill Livingstone, New York. Pages 1545-1585, 2000.

Gunderson LL, Tepper JE. Gastric Cancer. In Clinical Radiation Oncology, 2nd Edition. (Ed) Gunderson LL and Tepper JE. Churchill Livingstone/Elsevier. In Press.

Henning GT, Schild SE, Stafford SL, Donohue JH, Burch PA, Haddock MG, Gunderson LL. Results of irradiation or chemoirradiation for primary unresectable, locally recurrent, or grossly incomplete resection of gastric adenocarcinoma. Int J Rad Oncol Biol Phys. 46:109-118, 2000. [Abstract]

Henning G, Schild S, Stafford SL, Donohue JH, Burch P, Haddock MG, Trastek VF, Gunderson LL. Results of irradiation or chemoirradiation following resection of gastric adenocarcinoma. Int J Radiat Onc Biol Phys. 46:589-598, 2000. [Abstract]

Jessup JM, Gunderson LL, Greene FL et al. Stomach. In: Greene FL, Page AL, Fleming ID, et al editors. AJCC Cancer Staging Manual, 6th ed. New York: Springer; 2002, p. 99-106.

Macdonald JS, Smalley S, Benedetti J, Estes N, Haller DG, Ajani JA, Gunderson LL, Jessup M, Martenson JA. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. NEJM 345:725-730, 2001. [Abstract]

Smalley S, Gunderson L, Tepper J, Martenson J, Minsky B, Willett C, Rich T. Gastric surgical adjuvant radiotherapy - rationale and treatment implementation. Int J Rad Oncol Biol Phys. 52:283-293, 2002. [Abstract]

Tepper J, Gunderson LL. Radiation treatment parameters in the adjuvant postoperative therapy of gastric cancer. In Gastric Cancer. (Ed) J Tepper. Sem Rad Oncol 12:187-195, 2002. [Abstract]

Willett C, Gunderson LL. Stomach. In Principles and Practice of Radiation Oncology, 4th Edition. (Ed) C Perez, L Brady, E Halperin, R Schmidt-Ullrich. Lippincott/Williams & Wilkins. Pp 1554-1573, 2003.

Xiong HQ, Gunderson LL, Yao J, Ajani JA. Chemoradiation for resectable gastric cancer. Lancet Oncology. 4:495-505, 2003. [Abstract]