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Fuchs' Endothelial Dystrophy

Overview

Mayo Clinic offers all available treatment options and the latest technology for diagnosing Fuchs' endothelial dystrophy. Many doctors refer patients to Mayo Clinic because of Mayo's expertise in the coordinated management of this condition. Mayo ophthalmologists (eye doctors) have extensive experience treating patients who have Fuchs'endothelial dystrophy and are specially trained in corneal diseases, in addition to general ophthalmology.

Diagnosis

Fuchs'endothelial dystrophy is diagnosed through a thorough eye exam and testing. The ophthalmologist asks about symptoms that can include eye pain, blurry vision (particularly when waking up), variations in vision throughout the day, increased light sensitivity, and the presence of glare or halos. The doctor looks for swelling or tiny bumps (guttae) in the cornea. Special equipment is available to precisely measure the cornea's shape, clarity and thickness.

Treatment Options

Mayo Clinic offers all available treatment options for Fuchs' endothelial dystrophy. Treatment depends on the stage of the condition and may include:

  • Eyedrops or ointments to reduce fluid in the cornea.
  • Use of a warm hair dryer, held at arm's length or directed across the face two or three times a day to evaporate excess fluid in the cornea.
  • Soft contact lenses to temporarily reduce discomfort.
  • Surgery to cover the cornea with a thin membrane (conjunctival flap) to reduce pain.
  • Cornea transplant

About Fuchs' Endothelial Dystrophy

Fuchs' endothelial dystrophy is a slowly progressive hereditary disorder that affects the cornea (the transparent structure at the front of the eye). The condition causes the cells that line the inner surface (endothelium) of the cornea to slowly deteriorate and decrease in number. When the endothelial cells do not work properly or deteriorate, fluid builds up in the cornea and the cornea becomes thick, swollen and cloudy. In advanced stages of the disorder, painful tiny blisters form on the cornea's surface. The disorder can eventually lead to blindness.

Signs and symptoms of Fuchs' endothelial dystrophy usually appear and affect vision after age 50, although some people may notice signs in their 30s and 40s. The exact cause of the condition is unknown. Typically, women are more likely than men to have the disease.

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