Lutetium Lu 177 Dotatate (Intravenous Route)

Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

1. Agitation
2. anxiety
3. black, tarry stools
4. bleeding gums
5. blood in the urine or stools
6. blurred vision
7. chills
8. cold sweats
9. confusion
10. cool, pale skin
11. cough
12. decreased urine output
13. diarrhea
14. difficulty in breathing
15. dizziness
16. dry mouth
17. feeling of warmth
18. fever
19. flushed, dry skin
20. fruit-like breath odor
21. headache
22. hoarseness
23. hostility
24. increased hunger
25. increased thirst
26. increased urination
27. irritability
28. joint pain, stiffness, or swelling
29. loss of appetite
30. loss of consciousness
31. lower back, side, arm, leg, or stomach pain
32. mood changes
33. mood or mental changes
34. muscle cramps in the hands, arms, feet, legs, or face
35. muscle pain or twitching
36. nausea
37. nervousness
38. nightmares
39. numbness and tingling around the mouth, lips, hands, fingertips, or feet
40. painful or difficult urination
41. pale skin
42. pinpoint red spots on the skin
43. pounding in the ears
44. rapid weight gain
45. redness of the face, neck, arms, and occasionally, upper chest
46. restlessness
47. seizures
48. shakiness
49. slow, fast, or irregular heartbeat
50. slurred speech
51. sore throat
52. sweating
53. swelling of the face, feet, lower legs, ankles, or hands
54. tremor
55. troubled breathing
56. troubled breathing with exertion
57. ulcers, sores, or white spots in the mouth
58. unexplained weight loss
59. unusual bleeding or bruising
60. unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
61. vomiting
62. weakness or heaviness of the legs

Less common

1. Bone pain
2. chest pain or discomfort
3. dilated neck veins
4. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
5. extreme tiredness or weakness
6. irregular breathing
7. pain or discomfort in the arms, jaw, back, or neck
8. swollen glands

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

1. Constipation
2. decreased appetite
3. hair loss or thinning of the hair
4. loss or change in taste

Less common

1. Difficulty in moving
2. neck pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

• Precautions

Portions of this document last updated: Feb. 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.