Before Using

Drug information provided by: Merative, Micromedex®

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Demecarium, echothiophate, or isoflurophate can cause serious side effects in any patient. When this medicine is used for a long time, eye cysts may occur. These eye cysts occur more often in children than in adults. Therefore, it is especially important that you discuss with the child's doctor the good that this medicine may do as well as the risks of using it.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of these medicines in the elderly with use in other age groups. However, demecarium, echothiophate, or isoflurophate can cause serious side effects in any patient.

Pregnancy

Because of the toxicity of these medicines in general, demecarium, echothiophate, and isoflurophate are not recommended during pregnancy.

Breastfeeding

Demecarium, echothiophate, and isoflurophate may be absorbed into the body. These medicines are not recommended during breast-feeding, because they may cause unwanted effects in nursing babies. It may be necessary for you to use another medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Albuterol
  • Bimatoprost
  • Ceritinib
  • Clonidine
  • Cobicistat
  • Crizotinib
  • Darunavir
  • Desvenlafaxine
  • Diltiazem
  • Dronedarone
  • Duloxetine
  • Epinephrine
  • Escitalopram
  • Fenoldopam
  • Fingolimod
  • Fluoxetine
  • Formoterol
  • Indacaterol
  • Iohexol
  • Lacosamide
  • Latanoprost
  • Levalbuterol
  • Olodaterol
  • Oxymetazoline
  • Paroxetine
  • Ponesimod
  • Rivastigmine
  • Salmeterol
  • Sertraline
  • Tafluprost
  • Tegafur
  • Terbutaline
  • Thimerosal
  • Travoprost
  • Unoprostone
  • Verapamil
  • Vilanterol

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

  • Asthma or
  • Epilepsy or
  • Heart disease or
  • High or low blood pressure (severe) or
  • Myasthenia gravis or
  • Overactive thyroid or
  • Parkinsonism or
  • Stomach ulcer or other stomach problems or
  • Urinary tract blockage—If this medicine is absorbed into the body, it may make the condition worse.
  • Down's syndrome (Trisomy21)—This medicine may cause these children to become hyperactive.
  • Eye disease or problems (other)—May increase absorption of this medicine into the body or this medicine may make the condition worse

Portions of this document last updated: Feb. 01, 2024

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