Eosinophilic Esophagitis

Research

Mayo Clinic is a leader in eosinophilic esophagitis research and actively researches eosinophilic disorders. Mayo researchers have tested the effects of many medications on treatment, including:

• Steroids
• Asthma medications
• Acid-blocking medications

Clinical trials are under way to study long-term management and remission of eosinophilic esophagitis.

Researchers at Mayo were the first to recommend that everyone with problems swallowing (dysphagia) have a biopsy to test for eosinophils, in addition to an upper endoscopy. Mayo was among the first medical centers in the United States to publish research demonstrating how the number of cases of the disease has increased more than tenfold in the last 30 years. Mayo doctors also have shown through their research the safety and effectiveness of endoscopic dilation on esophageal narrowing (strictures) in people who have eosinophilic esophagitis.

Mayo's Allergic Diseases Research Laboratory investigates the mechanisms of common airway and skin diseases. The lab focuses on and studies types of immune (white blood) cells, especially eosinophils. The laboratories in Clinical Immunology and Immunotherapeutics, Immunology, and Gastroenterology and Hepatology also are involved in research on eosinophilic disorders.

Publications

See a list of publications by Mayo Clinic doctors about eosinophilic esophagitis on PubMed, a service of the National Library of Medicine.