Ehlers-Danlos Syndrome

Types

All types of EDS affect the joints, and most also affect the skin. At Mayo Clinic, teams of experienced and highly trained specialists work with patients to identify the most appropriate treatment for each type of EDS.

Ehlers-Danlos syndrome is classified according to the signs and symptoms exhibited by patients.

Arthrochalasia

Congenital hip dislocation
Severe joint hypermobility (extreme flexibility)
Skin hyperextensibility (extreme stretchiness)
Frail skin tissue

Classical

Skin hyperextensibility
Joint hypermobility
Smooth, velvety skin
Widened scars over pressure points such as knees

Dermatosparaxis

Severe skin fragility
Soft, doughy and saggy skin

Hypermobility

Joint hypermobility
Joint dislocations
Chronic joint and limb pain
Smooth, velvety skin

Kyphoscoliosis

Joint laxity and weak muscle tone at birth
Delayed gross motor development
Progressive, severe symptoms
Possibility of spontaneous arterial rupture

Vascular

Ruptures of the arteries, organs or uterus
Thin, translucent skin over the chest and abdomen
Extensive bruising