Proper Use

Drug information provided by: Micromedex

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not stop taking this medicine without checking with your doctor first.

This medicine comes with a patient information sheet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Keep taking zidovudine for the full time of treatment, even if you begin to feel better. Only take medicine that your doctor has prescribed specifically for you. Do not share your medicine with other people.

For patients using zidovudine oral solution:

  • Shake the oral solution before use. Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. If you need help in planning the best times to take your medicine, check with your doctor.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For HIV infection:
    • For oral dosage forms (capsules, solution, and tablets):
      • Adults—600 milligrams (mg) a day in divided doses in combination with other anti-virus medicine.
      • Children and infants 4 weeks of age and older—Dose is based on body weight or body size and must be determined by your child's doctor. The recommended dose is 18 to 24 milligrams (mg) per kilogram (kg) per day of body weight or 600 mg per day or 480 milligrams per square meter of body surface area (mg/m²) a day in divided doses.
  • To help prevent pregnant women from passing HIV to their babies during pregnancy and at birth:
    • For oral dosage form (capsules):
      • Pregnant women (after 14 weeks of pregnancy, up to the start of labor)—100 milligrams (mg) five times a day, 200 mg every eight hours, or 300 mg every twelve hours until the start of labor.
    • For oral dosage form (solution):
      • Pregnant women (after 14 weeks of pregnancy, up to the start of labor)—100 milligrams (mg) five times a day, 200 mg every eight hours, or 300 mg every twelve hours until the start of labor.
      • Newborn infants—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 milligrams (mg) per kilogram (kg) (0.9 mg per pound) of body weight every six hours starting within eight to twelve hours of birth and continuing through 6 weeks of age.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.