Dosing

The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.

Adults (18 years and older)

Daily doses of 20-30 grams of whey protein have been used, without exceeding 1.2 grams per kilogram of body weight. A whey-containing protein shake after workouts has been used.

For reducing appetite, whey protein has been taken by mouth in single doses, doses of up to 60 grams, or 0.5 grams per kilogram of body weight in the form of Fonterra WPI 894 or BiPRO®. Whey protein has been added to yogurt as a single dose. Whey protein has been taken by mouth in the form of Lacprodan® DI-9213, containing 1,000 millijoules of energy.

For bone density, milk containing 30-40 milligrams of milk basic protein has been taken by mouth for 6-8 months. Doses of 30-60 milligrams of whey basic protein have been taken by mouth daily for 24 weeks. A dose of 250 milliliters of a skim milk-based drink containing 30 grams of whey protein has been taken by mouth daily for two years.

For bronchospasm (abnormal lung muscle contraction), 30 grams of denatured whey protein has been taken by mouth daily for eight weeks.

For cancer, 30 grams of whey protein has been taken by mouth daily for six months.

For heart disease risk, up to 60 grams of whey protein has been taken by mouth 1-2 times daily for 4-36 weeks. A dose of 45 grams of whey protein isolate has been taken by mouth as a single dose at breakfast. Milkshakes containing 45 grams of whey isolate (Lacprodan®-DI-9224) or whey hydrolysate (Lacprodan®-DI-3065) have been taken by mouth as single doses. A single dose of 5 grams of a whey-derived peptide (NOP-47) has been taken by mouth daily. Up to 15 grams of malleable protein matrix (Wheygurte™) has been taken by mouth twice daily for three months.

For chronic lung conditions, 12 grams of whey protein has been taken by mouth twice daily for six weeks. A dose of 20 grams of pressurized whey in 120 milliliters of applesauce has been taken by mouth for 16 weeks.

For cystic fibrosis (mucus build-up in the lungs), whey in applesauce has been taken by mouth in a dose of 40 grams daily for 28 days. A dose of 10 grams of whey protein isolate (ImmunocalTM) has been taken by mouth twice daily for three months.

For dehydration, a drink containing 15 grams per liter of Impact whey protein has been taken by mouth over one hour as a single dose.

For diabetes, whey protein has been taken by mouth as a single dose in the following forms and doses: 45-55 grams, taken alone or added to soup or a potato, and single doses added to meals or drinks. Doses of 5-10 grams of glycemic index-lowering peptide fraction (GILP) from whey as a single dose have been taken by mouth. Whey protein has been taken by mouth in the form of Peptamen®.

For improving phosphate levels in people undergoing dialysis, 30 grams of a low-phosphate and low-potassium whey protein concentrate have been taken by mouth daily for three months.

For improved muscle strength, whey protein has been taken by mouth in the following doses and/or forms: up to 45 grams mixed with Gatorade®, three times weekly for up to 14 weeks; 1.2 grams per kilogram alone or mixed with sucrose powder, daily for six weeks; 30 grams in sachets mixed with food or drinks, twice daily for 36 weeks; 1.5 grams per kilogram of hydrolyzed whey isolate daily for 10 weeks; 33 grams as part of a protein bar, daily for nine weeks; 1.5 grams per kilogram immediately after exercise and four times daily for 14 days; 15 grams before and after exercise for 21 weeks; 1.0 gram per kilogram of whey protein powder daily for 14 weeks; and a dairy supplement containing whey protein, twice daily for eight weeks.

For exercise performance and recovery, whey protein has been taken by mouth in the following doses and/or forms: single doses of 2 percent whey hydrolysate in a test drink or 25 grams in flavored water; 0.4 grams per kilogram hourly with sucrose; 44 grams of orange-flavored Maximuscle Promax™ in divided doses before and after exercise, then twice daily for three days; 42 grams before and after exercise; 1.2-1.5 grams per kg daily with strength training.

For hearing loss, an undenatured whey protein supplement rich in glutathione has been taken by mouth.

For H. pylori infection, 2.5 grams of immune whey protein concentrate (WPC-80) has been taken by mouth three times daily for 28 days.

For liver inflammation, 20 grams of undenatured cysteine-rich whey protein isolate has been taken by mouth in two divided doses mixed with water, daily for 12 weeks. A dose of 12 grams of whey protein added to mousse has been taken by mouth twice daily for 12 weeks.

For HIV, the following doses and/or forms of whey protein have been taken by mouth: 40-45 grams 1-2 times daily for 2-12 weeks; 8.4 grams of Immunocal™ daily for four weeks, then 19.6 grams daily for four weeks, then 28 grams daily for one week, and finally 39.2 grams daily for three weeks; 8.4-84 grams of whey protein daily; 2.4 grams per kilogram daily in a high-calorie formula; and 42-84 grams daily in a glutamine-enriched formula.

For high blood pressure, 125-250 milliliters of drinks supplemented with whey peptides or whey protein (Alacen®) have been taken by mouth daily for 12 weeks to two years. A dose of 20 grams of hydrolyzed whey protein or unmodified whey protein has been taken by mouth daily for six weeks.

For immune function, 5 grams of whey protein has been taken by mouth three times daily for eight weeks.

For nutrition (protein source), 0.8 grams per kilogram of protein (with 50 percent being whey protein) has been taken by mouth daily for 15 days. Up to 15 grams of whey protein has been taken by mouth as a single dose. Doses of 0.3 grams per kilogram of whey protein to 0.48 grams of casein have been taken by mouth as a single dose.

For psoriasis, 5 grams of XP-828L whey protein extract has been taken by mouth daily for 56 days.

For weight loss, the following forms and/or doses of whey protein have been taken by mouth: Prolibra™ for 12 weeks; 240 kilocalories daily for two months; 25 grams twice daily for 12 weeks; 1 liter of a milk-based whey drink, daily for 12 weeks; 51-52 gram packets containing 27.5 grams of a cheese-derived whey protein supplement (whey protein concentrate-80), twice daily for 23 weeks; and Designer Whey® for eight weeks.

For dental plaque, whey protein toothpaste and tooth powder (0-20 percent) have been used for eight weeks.

Children (under 18 years old)

For allergies, 10 grams of whey protein (HMS90™) have been taken by mouth twice daily for one month. Formulas containing hydrolyzed whey proteins have been taken by mouth for the first four months in infants.

For reducing appetite, 1 gram per kilogram or up to 50 grams of whey protein have been taken by mouth as a single dose.

For burns, diets supplemented with ultrafiltered whey protein have been taken by mouth.

For cerebral palsy, 2.8 grams per 100 milliliters of hydrolyzed whey protein has been taken by mouth as a single meal via feeding pump.

For cystic fibrosis, 20 grams of pressurized whey in applesauce has been taken by mouth for 28 days. A dose of 10 grams of whey protein has been taken by mouth twice daily for three months.

For eczema, partially or extensively hydrolyzed whey infant formulas have been taken by mouth.

For HIV, whey protein has been taken by mouth once or twice daily for four months, with the first dose representing 20 percent of the total daily protein requirement, increasing by 10 percent each month over three months, until forming 50 percent of the total daily protein requirement.

For mitochondrial diseases, 10 grams of ProtherSOD® have been taken by mouth daily for 60 days.

For infection, 0.3 grams per kilogram of Beneprotein® have been injected into the vein every morning for up to 28 days.

This evidence-based monograph was prepared by The Natural Standard Research Collaboration

www.naturalstandard.com