Interactions with Drugs
Vitamin D may affect blood sugar levels. Caution is advised when using medications that may also affect blood sugar. People taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.
Vitamin D may affect blood pressure. Caution is advised in people taking drugs that affect blood pressure.
Vitamin D may interfere with the way the body processes certain drugs using the liver's "cytochrome P450" enzyme system. As a result, the levels of these drugs may be altered in the blood, and may cause altered effects or potentially serious adverse reactions. People using any medications should check the package insert, and speak with a qualified healthcare professional, including a pharmacist, about possible interactions.
Vitamin D may also interact with acitretin, agents that affect the immune system, agents that bind bile, agents that prevent seizures, agents that promote urination, agents that treat heart disorders, agents that treat retrovirus infections (HIV), aluminum, antacids, antiandrogens, anti-asthma agents, antibiotics, anticancer agents, anti-inflammatories, birth control, bisphosphonates, calcipotriene, calcium salts, cardiac glycosides, cholesterol-lowering agents (such as HMG-CoA reductase inhibitors), cimetidine, cinacalcet, corticosteroids, cyclosporine, dental agents, diltiazem, exemestane, fat-soluble agents, fertility agents, heparins, hormonal agents, insulin, interferon, ketoconazole, laxatives, lung agents, mineral oil, nervous system agents, opioids, orlistat, osteoporosis agents, pain relievers, rifampin, sevelamer, skin agents, stomach agents, sunscreens, tar-based shampoo, thyroid hormone antagonists, vaccines, and vitamin D receptor agonists.
Interactions with Herbs and Dietary Supplements
Vitamin D may affect blood sugar levels. Caution is advised when using herbs or supplements that may also affect blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.
Vitamin D may affect blood pressure. Caution is advised in people taking herbs or supplements that affect blood pressure.
Vitamin D may interfere with the way the body processes certain herbs or supplements using the liver's "cytochrome P450" enzyme system. As a result, the levels of other herbs or supplements may be altered in the blood. It may also alter the effects that other herbs or supplements possibly have on the P450 system.
Vitamin D may also interact with aluminum, antacids, antiandrogenics, anti-asthma herbs and supplements, antibacterials, anticancer herbs and supplements, anti-inflammatories, athletic performance enhancers, birth control, calcium, cardiac glycosides, cholesterol-lowering herbs and supplements, dental herbs and supplements, fat-soluble herbs and supplements, fertility herbs and supplements, herbs and supplements that affect the immune system, herbs and supplements that decrease calcium, herbs and supplements that prevent seizures, herbs and supplements that promote urination, herbs and supplements that treat heart disorders, hormonal herbs and supplements, hormone replacement therapy, laxatives, lung herbs and supplements, magnesium, micronutrients, mineral oil, nervous system herbs and supplements, osteoporosis herbs and supplements, pain relievers, silicon, stomach herbs and supplements, sunscreens, vitamin A, and vitamin K.
This evidence-based monograph was prepared by The Natural Standard Research Collaboration