Description and Brand Names

Drug information provided by: Micromedex

Descriptions


Sotalol injection is used to control rapid heartbeats and abnormal heart rhythms that are serious or life-threatening. The injection may also be used when patients are not able to take the oral form.

Sotalol is a beta-blocker and antiarrhythmic. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and at a regular rhythm.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Solution

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of sotalol injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of sotalol injection in elderly patients. However, elderly patients are more likely to have age-related kidney disease, which may require an adjustment in the dose for patients receiving sotalol injection.

Pregnancy

Information about this sotalol-intravenous-route
Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Amifampridine
  • Bepridil
  • Cisapride
  • Dronedarone
  • Fingolimod
  • Grepafloxacin
  • Levomethadyl
  • Mesoridazine
  • Pimozide
  • Piperaquine
  • Sparfloxacin
  • Terfenadine
  • Thioridazine
  • Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acecainide
  • Acetazolamide
  • Albuterol
  • Amiloride
  • Amiodarone
  • Amisulpride
  • Amitriptyline
  • Amoxapine
  • Apomorphine
  • Aprindine
  • Arformoterol
  • Arsenic Trioxide
  • Artemether
  • Asenapine
  • Astemizole
  • Azimilide
  • Azithromycin
  • Azosemide
  • Bambuterol
  • Bedaquiline
  • Bemetizide
  • Bendroflumethiazide
  • Benzthiazide
  • Bretylium
  • Bumetanide
  • Canrenoate
  • Chloral Hydrate
  • Chloroquine
  • Chlorpromazine
  • Chlorthalidone
  • Ciprofloxacin
  • Citalopram
  • Clarithromycin
  • Clenbuterol
  • Clomipramine
  • Clonidine
  • Clopamide
  • Clozapine
  • Colterol
  • Crizotinib
  • Cyclobenzaprine
  • Cyclothiazide
  • Dasatinib
  • Desipramine
  • Dibenzepin
  • Diltiazem
  • Disopyramide
  • Dofetilide
  • Dolasetron
  • Domperidone
  • Doxepin
  • Dronedarone
  • Droperidol
  • Enflurane
  • Epinephrine
  • Erythromycin
  • Ethacrynic Acid
  • Etozolin
  • Fenoldopam
  • Fenoterol
  • Fenquizone
  • Flecainide
  • Fluconazole
  • Fluoxetine
  • Formoterol
  • Foscarnet
  • Furosemide
  • Gatifloxacin
  • Gemifloxacin
  • Granisetron
  • Halofantrine
  • Haloperidol
  • Halothane
  • Hexoprenaline
  • Hydrochlorothiazide
  • Hydroflumethiazide
  • Ibutilide
  • Iloperidone
  • Imipramine
  • Indacaterol
  • Indapamide
  • Isoetharine
  • Isoflurane
  • Isradipine
  • Itraconazole
  • Ivabradine
  • Ketoconazole
  • Lapatinib
  • Levalbuterol
  • Levofloxacin
  • Lidocaine
  • Lidoflazine
  • Lopinavir
  • Lorcainide
  • Lumefantrine
  • Mannitol
  • Mefloquine
  • Metaproterenol
  • Methadone
  • Metolazone
  • Mifepristone
  • Moricizine
  • Moxifloxacin
  • Nilotinib
  • Norfloxacin
  • Nortriptyline
  • Octreotide
  • Ofloxacin
  • Ondansetron
  • Paliperidone
  • Pasireotide
  • Pazopanib
  • Pentamidine
  • Perflutren Lipid Microsphere
  • Pirbuterol
  • Piretanide
  • Polythiazide
  • Posaconazole
  • Prilocaine
  • Probucol
  • Procainamide
  • Procaterol
  • Prochlorperazine
  • Promethazine
  • Propafenone
  • Protriptyline
  • Quetiapine
  • Quinethazone
  • Quinidine
  • Quinine
  • Ranolazine
  • Reproterol
  • Risperidone
  • Ritodrine
  • Salmeterol
  • Saquinavir
  • Sematilide
  • Sertindole
  • Sodium Phosphate
  • Sodium Phosphate, Dibasic
  • Sodium Phosphate, Monobasic
  • Solifenacin
  • Sorafenib
  • Sotalol
  • Spiramycin
  • Spironolactone
  • Sulfamethoxazole
  • Sultopride
  • Sunitinib
  • Tedisamil
  • Telavancin
  • Telithromycin
  • Terbutaline
  • Tetrabenazine
  • Ticrynafen
  • Tizanidine
  • Toremifene
  • Torsemide
  • Trazodone
  • Tretoquinol
  • Triamterene
  • Trichlormethiazide
  • Trifluoperazine
  • Trimethoprim
  • Trimipramine
  • Tulobuterol
  • Vandetanib
  • Vardenafil
  • Vasopressin
  • Vemurafenib
  • Verapamil
  • Vilanterol
  • Vinflunine
  • Voriconazole
  • Xipamide
  • Zolmitriptan
  • Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Abarelix
  • Acarbose
  • Aceclofenac
  • Acemetacin
  • Acetohexamide
  • Acetyldigoxin
  • Alfuzosin
  • Amlodipine
  • Amtolmetin Guacil
  • Arbutamine
  • Aspirin
  • Benfluorex
  • Bromfenac
  • Bufexamac
  • Bunazosin
  • Celecoxib
  • Chlorpropamide
  • Choline Salicylate
  • Clonixin
  • Deslanoside
  • Dexibuprofen
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Digitoxin
  • Digoxin
  • Dipyrone
  • Doxazosin
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Felodipine
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Flufenamic Acid
  • Flurbiprofen
  • Gliclazide
  • Glimepiride
  • Glipizide
  • Gliquidone
  • Glyburide
  • Guar Gum
  • Ibuprofen
  • Ibuprofen Lysine
  • Indomethacin
  • Insulin
  • Insulin Aspart, Recombinant
  • Insulin Glulisine
  • Insulin Lispro, Recombinant
  • Ketoprofen
  • Ketorolac
  • Lacidipine
  • Lercanidipine
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Manidipine
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Metformin
  • Methyldopa
  • Metildigoxin
  • Mibefradil
  • Miglitol
  • Morniflumate
  • Moxisylyte
  • Nabumetone
  • Naproxen
  • Nepafenac
  • Nicardipine
  • Nifedipine
  • Niflumic Acid
  • Nilvadipine
  • Nimesulide
  • Nimodipine
  • Nisoldipine
  • Nitrendipine
  • Oxaprozin
  • Oxyphenbutazone
  • Parecoxib
  • Phenoxybenzamine
  • Phentolamine
  • Phenylbutazone
  • Piketoprofen
  • Piroxicam
  • Pranidipine
  • Pranoprofen
  • Prazosin
  • Proglumetacin
  • Propyphenazone
  • Proquazone
  • Repaglinide
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Sodium Salicylate
  • St John's Wort
  • Sulindac
  • Tamsulosin
  • Tenoxicam
  • Terazosin
  • Tiaprofenic Acid
  • Tolazamide
  • Tolbutamide
  • Tolfenamic Acid
  • Tolmetin
  • Trimazosin
  • Troglitazone
  • Urapidil
  • Valdecoxib

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Angina (severe chest pain) or
  • Heart attack, recent or
  • Heart disease or
  • Heart failure, history of or
  • Hypotension (low blood pressure)—Use with caution. May make these conditions worse.
  • Asthma or
  • AV block (type of abnormal heart rhythm), with no pacemaker or
  • Bradycardia (slow heartbeat) or
  • Breathing problems or
  • Cardiogenic shock or
  • Heart failure, uncontrolled or
  • Heart rhythm problems (e.g., congenital long QT interval) or
  • Hypokalemia (low potassium in the blood) or
  • Hypomagnesemia (low magnesium in the blood) or
  • Kidney disease, severe or
  • Sick sinus syndrome (type of abnormal heart rhythm), with no pacemaker—Should not be used in patients with these conditions.
  • Diabetes or
  • Hyperthyroidism (overactive thyroid) or
  • Hypoglycemia (low blood sugar)—Use with caution. May cover up some of the symptoms of these diseases, such as a fast heartbeat.
  • Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use

A nurse or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.

Tell your doctor or nurse right away if you develop pain or swelling at the site where the needle is placed.

Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Precautions

It is very important that your doctor check your progress while you are receiving this medicine to make sure the medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. These symptoms are more likely to occur when you begin using this medicine, or when the dose is increased. Getting up slowly may help.

Sotalol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; weight gain; or wheezing.

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are receiving this medicine.

This medicine may cause changes in your blood sugar levels. Also, this medicine may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems or if you notice a change in the results of your blood or urine sugar tests.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Blurred vision
  2. chest pain or discomfort
  3. confusion
  4. difficult or labored breathing
  5. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  6. fast, irregular, pounding, or racing heartbeat or pulse
  7. increased sweating
  8. shortness of breath
  9. slow or irregular heartbeat
  10. sweating
  11. swelling
  12. tightness in the chest
  13. unusual tiredness or weakness
  14. wheezing

Less common

  1. Arm, back, or jaw pain
  2. body aches or pain
  3. chest tightness or heaviness
  4. chills
  5. cold hands and feet
  6. cough
  7. decreased urine output
  8. diarrhea
  9. difficulty with breathing
  10. difficulty with speaking
  11. dilated neck veins
  12. dizziness
  13. double vision
  14. ear congestion
  15. extreme fatigue
  16. fainting
  17. fever
  18. general feeling of discomfort or illness
  19. headache
  20. inability to move the arms, legs, or facial muscles
  21. inability to speak
  22. irregular breathing
  23. joint pain
  24. loss of appetite
  25. loss of voice
  26. muscle aches and pains
  27. nasal congestion
  28. nausea
  29. nervousness
  30. noisy breathing
  31. pounding in the ears
  32. runny nose
  33. shivering
  34. slow speech
  35. sneezing
  36. sore throat
  37. swelling of the face, fingers, feet, or lower legs
  38. trouble sleeping
  39. troubled breathing
  40. vomiting
  41. weight gain

Incidence not known

  1. Black, tarry stools
  2. bleeding gums
  3. blood in the urine or stools
  4. blue lips and fingernails
  5. coughing that sometimes produces a pink frothy sputum
  6. difficult, fast, or noisy breathing, sometimes with wheezing
  7. increased sweating
  8. painful or difficult urination
  9. pale skin
  10. pinpoint red spots on the skin
  11. sores, ulcers, or white spots on the lips or in the mouth
  12. swelling in the legs and ankles
  13. swollen glands
  14. unusual bleeding or bruising

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Acid or sour stomach
  2. belching
  3. heartburn
  4. indigestion
  5. lack or loss of strength
  6. sleeplessness
  7. stomach discomfort, upset, or pain
  8. unable to sleep

Less common

  1. Abdominal or stomach distension
  2. abnormal ejaculation
  3. back pain
  4. bloated feeling
  5. blurred or loss of vision
  6. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  7. decreased appetite
  8. decreased sexual performance or desire
  9. depression
  10. disturbed color perception
  11. double vision
  12. excess air or gas in the stomach or intestines
  13. full feeling
  14. halos around lights
  15. mood changes
  16. muscle or bone pain
  17. night blindness
  18. overbright appearance of lights
  19. passing gas
  20. rash
  21. tunnel vision

Incidence not known

  1. Crying
  2. depersonalization
  3. difficulty with moving
  4. dysphoria
  5. euphoria
  6. feeling of constant movement of self or surroundings
  7. hair loss
  8. increased sensitivity of the skin to sunlight
  9. itching skin
  10. lack of coordination
  11. mental depression
  12. muscle aching or cramping
  13. muscle pains or stiffness
  14. pain, itching, burning, swelling, or a lump under your skin where the needle is placed
  15. paranoia
  16. quick to react or overreact emotionally
  17. rapidly changing moods
  18. redness or other discoloration of the skin
  19. sensation of spinning
  20. severe sunburn
  21. swollen joints
  22. thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.