Dosing

The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.

Adults (18 years and older)

Saw palmetto has been taken as sterol and fatty acid extracts (such as LSESR), berries (ground, dried, whole, or pulp), tincture, fluid extract, or tea. Teas prepared from saw palmetto berries may be ineffective because the purported active constituents are water-insoluble.

For enlarged prostate (benign prostatic hypertrophy), a range of 100-960 milligrams of sabal or Serenoa repens extract has been taken by mouth daily for up to 18 months. A dose of 320 milligrams of saw palmetto extract (e.g., Permixon®, Serendar, Talso®), in one dose or two divided doses (80-90% liposterolic content), by mouth daily for up to six months, has been taken in numerous studies. Dosing regimens of 160 milligrams of saw palmetto twice daily for eight weeks (PA109), nine weeks, and 12 weeks (Prostaserene®) have been taken by mouth. Reports suggest that 160 milligrams once daily by mouth may be as effective as twice daily by mouth. Libeprosta® has been taken as two 80 milligram tablets twice or three times daily by mouth. A dose of 640 milligrams of saw palmetto has also been taken by mouth daily for an unknown length of time. A dose of 640 milligrams of saw palmetto extract has been applied to the rectum once daily for 12 weeks.

In preparation for surgery, pretreatment with 320 milligrams of Serenoa repens (Permixon®) has been taken by mouth daily for at least eight weeks before surgery.

To treat prostate inflammation, 320 milligrams of prostamol (Sabal serrulata plant extract) has been taken by mouth. Also, 320 milligrams of Serenoa repens has been taken by mouth daily for eight weeks.

Children (younger than 18 years)

There is no proven safe or effective dose for saw palmetto in children.

This evidence-based monograph was prepared by The Natural Standard Research Collaboration

www.naturalstandard.com