The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.
Adults (18 years and older)
Red yeast rice (RYR) should be taken with food. A dose of 1,200 milligrams of red yeast powder in the form of capsules has been taken by mouth twice daily with food. In Asia, the average consumption of naturally occurring RYR is 14-55 grams daily.
To treat coronary heart disease, 1,200-2,400 milligrams of Xuezhikang has been taken by mouth daily for 2-12 weeks. Xuezhikang has also been taken by mouth at doses of 0.3-0.6 grams twice daily for 4-4.5 years on average (range: 0.5-7 years). Xuezhikang has been taken by mouth at a dose of 1,200 milligrams daily for 12 weeks to 24 months.
To treat diabetes, two capsules of 300 milligrams of Monascus extract have been taken by mouth for eight weeks.
To treat high cholesterol, 1,200-2,400 milligrams of Cholestin® has been taken by mouth 1-2 times daily for up to 12 weeks. Doses of 600-1,800 milligrams RYR have been taken by mouth up to three times daily for 8-24 weeks. Two capsules of 300 milligrams of RYR product have been taken by mouth daily for 1-3 cycles of eight weeks each. Doses of 600-3,600 milligrams of Xuezhikang/RYR have been taken by mouth 1-2 times daily for up to one year. A dose of 2-4 capsules of Xuezhikang has been taken by mouth twice daily for 8-12 weeks. A dose of five capsules of 0.5 grams of Xuezhikang has been taken by mouth twice daily for two months. Doses of 0.6-3.6 grams of RYR extract have been taken by mouth daily for four weeks to 4.5 years. Doses of 0.6-1.2 grams of Monascus purpureus rice preparation have been taken by mouth 1-2 times daily for eight weeks to one year, with dose adjustment depending on cholesterol levels and tolerance. Five Zhitai capsules have been taken by mouth twice daily (for a dose of five grams daily) for two months. Three Zhibituo tablets (0.35 grams each) have been taken by mouth three times daily for a total of 3.15 grams daily. One to two capsules of Xuezhikang have been taken by mouth 2-3 times daily for up to 24 weeks. Four capsules of RYR (HypoCol®, Wearnes Biotech & Medicals Pte, Singapore) have been taken by mouth daily for 16 weeks.
To treat fatty liver, 0.6 grams of RYR have been taken by mouth twice daily for 12 weeks.
Children (younger than 18 years)
There is no proven safe or effective dose for RYR in children.
This evidence-based monograph was prepared by The Natural Standard Research Collaboration