Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Inderal

Descriptions


Propranolol injection is used to control fast heartbeats and abnormal heart rhythms .

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and at a regular rhythm .

This medicine is available only with your doctor's prescription .

This product is available in the following dosage forms:

  • Solution

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of propranolol injection in the pediatric population. Safety and efficacy have not been established .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of propranolol injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require an adjustment of dosage in patients receiving propranolol injection .

Pregnancy

Information about this propranolol-intravenous-route
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Thioridazine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Albuterol
  • Amiodarone
  • Arformoterol
  • Bambuterol
  • Bupivacaine
  • Bupivacaine Liposome
  • Bupropion
  • Clenbuterol
  • Clonidine
  • Clozapine
  • Colterol
  • Crizotinib
  • Diatrizoate
  • Diltiazem
  • Dronedarone
  • Epinephrine
  • Eslicarbazepine Acetate
  • Fenoldopam
  • Fenoterol
  • Fingolimod
  • Fluoxetine
  • Formoterol
  • Haloperidol
  • Hexoprenaline
  • Indacaterol
  • Isoetharine
  • Levalbuterol
  • Lidocaine
  • Lomitapide
  • Mefloquine
  • Mepivacaine
  • Metaproterenol
  • Nilotinib
  • Olodaterol
  • Pirbuterol
  • Pixantrone
  • Prilocaine
  • Procaterol
  • Reproterol
  • Ritodrine
  • Salmeterol
  • Simeprevir
  • Terbutaline
  • Tocophersolan
  • Tretoquinol
  • Tulobuterol
  • Ulipristal
  • Verapamil
  • Vilanterol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acarbose
  • Aceclofenac
  • Acemetacin
  • Acetohexamide
  • Acetyldigoxin
  • Alfuzosin
  • Amlodipine
  • Amtolmetin Guacil
  • Arbutamine
  • Aspirin
  • Benfluorex
  • Bromfenac
  • Bufexamac
  • Bunazosin
  • Celecoxib
  • Chlorpromazine
  • Chlorpropamide
  • Cholestyramine
  • Choline Salicylate
  • Cimetidine
  • Clonixin
  • Deslanoside
  • Dexibuprofen
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Digitoxin
  • Digoxin
  • Dihydroergotamine
  • Dipyrone
  • Disopyramide
  • Doxazosin
  • Ergotamine
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Felodipine
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Flecainide
  • Floctafenine
  • Flufenamic Acid
  • Flurbiprofen
  • Fluvoxamine
  • Gliclazide
  • Glimepiride
  • Glipizide
  • Gliquidone
  • Glyburide
  • Guar Gum
  • Guggul
  • Ibuprofen
  • Ibuprofen Lysine
  • Indomethacin
  • Insulin
  • Insulin Aspart, Recombinant
  • Insulin Glulisine
  • Insulin Lispro, Recombinant
  • Ketoprofen
  • Ketorolac
  • Lacidipine
  • Lercanidipine
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Manidipine
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Metformin
  • Metildigoxin
  • Mibefradil
  • Miglitol
  • Morniflumate
  • Moxisylyte
  • Nabumetone
  • Naproxen
  • Nepafenac
  • Nicardipine
  • Nifedipine
  • Niflumic Acid
  • Nilvadipine
  • Nimesulide
  • Nimodipine
  • Nisoldipine
  • Nitrendipine
  • Oxaprozin
  • Oxyphenbutazone
  • Parecoxib
  • Phenoxybenzamine
  • Phentolamine
  • Phenylbutazone
  • Phenylephrine
  • Piketoprofen
  • Piperine
  • Piroxicam
  • Pranidipine
  • Pranoprofen
  • Prazosin
  • Proglumetacin
  • Propoxyphene
  • Propyphenazone
  • Proquazone
  • Quinidine
  • Repaglinide
  • Rifapentine
  • Rizatriptan
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Sertraline
  • Sodium Salicylate
  • St John's Wort
  • Sulindac
  • Tamsulosin
  • Tenoxicam
  • Terazosin
  • Tiaprofenic Acid
  • Tolazamide
  • Tolbutamide
  • Tolfenamic Acid
  • Tolmetin
  • Trimazosin
  • Troglitazone
  • Tubocurarine
  • Urapidil
  • Valdecoxib
  • Zileuton

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Tobacco

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Angina (severe chest pain)—May provoke chest pain if stopped too quickly .
  • Asthma or
  • Bradycardia (slow heartbeat) or
  • Heart block or
  • Heart failure—Should not use in patients with these conditions .
  • Diabetes or
  • Hyperthyroidism (overactive thyroid) or
  • Hypoglycemia (low blood sugar)—May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat .
  • Kidney disease or
  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body .
  • Lung disease (e.g., bronchitis, emphysema)—May cause difficulty with breathing in patients with this condition .
  • Wolff-Parkinson-White syndrome (rare heart condition)—May cause a very slow heartbeat in patients with this condition .

Proper Use

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins .

Precautions

Your doctor will only give you a few doses of this medicine until your condition improves, and then you will be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor .

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Blurred vision
  2. chest pain or discomfort
  3. confusion
  4. decreased urine output
  5. dilated neck veins
  6. dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  7. extreme fatigue
  8. irregular breathing
  9. lightheadedness, dizziness, or fainting
  10. shortness of breath
  11. slow or irregular heartbeat
  12. sweating
  13. swelling of face, fingers, feet, or lower legs
  14. tightness in chest
  15. troubled breathing
  16. unusual tiredness or weakness
  17. weight gain
  18. wheezing

Rare

  1. Blisters, hives, or itching
  2. fever and chills
  3. general feeling of discomfort or illness
  4. hair loss
  5. headaches
  6. muscle or joint pain
  7. skin rash
  8. sore throat
  9. swollen glands

Incidence not determined

  1. Abdominal pain, usually after eating a meal
  2. abdominal tenderness
  3. black, tarry stools
  4. blood in urine
  5. bloody nose
  6. bloody stools
  7. body aches or pain
  8. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  9. congestion
  10. constipation
  11. cough
  12. decreased awareness or responsiveness
  13. diarrhea
  14. difficult or labored breathing
  15. dryness or soreness of throat
  16. general feeling of tiredness or weakness
  17. heavier menstrual periods
  18. hoarseness
  19. lower back or side pain
  20. mimicry of speech or movements
  21. mutism
  22. nausea
  23. negativism
  24. no blood pressure or pulse
  25. noisy breathing
  26. painful or difficult urination
  27. paleness or cold feeling in fingertips and toes
  28. peculiar postures or movements, mannerisms, or grimacing
  29. pinpoint red or purple spots on skin
  30. rectal bleeding
  31. reddened skin
  32. runny nose
  33. severe sleepiness
  34. sores on the skin
  35. sores, ulcers, or white spots on lips or in mouth
  36. stopping of heart
  37. tender, swollen glands in neck
  38. tingling or pain in fingers or toes when exposed to cold
  39. trouble in swallowing
  40. unconsciousness
  41. unusual bleeding or bruising
  42. voice changes
  43. vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

  1. Decreased interest in sexual intercourse
  2. dry eyes
  3. inability to have or keep an erection
  4. loss in sexual ability, desire, drive, or performance
  5. pain of penis on erection
  6. skin irritation or rash, including rash that looks like psoriasis
  7. thinning of hair

Incidence not determined

  1. Confusion about identity, place, and time
  2. crying
  3. depersonalization
  4. disturbed color perception
  5. double vision
  6. dysphoria
  7. euphoria
  8. halos around lights
  9. loss of strength or energy
  10. loss of vision
  11. mental depression
  12. muscle weakness
  13. night blindness
  14. overbright appearance of lights
  15. paranoia
  16. quick to react or overreact emotionally
  17. rapidly changing moods
  18. seeing, hearing, or feeling things that are not there
  19. short-term memory loss
  20. sleeplessness
  21. trouble sleeping
  22. tunnel vision
  23. unable to sleep
  24. unusual drowsiness, dullness, or feeling of sluggishness
  25. vivid dreams

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.