Before Using

Drug information provided by: Micromedex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of posaconazole in teenagers 13 to 17 years of age. However, safety and efficacy have not been established in children younger than 13 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of posaconazole in the elderly.

Pregnancy

Information about this posaconazole-oral-route
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Alfuzosin
  • Amifampridine
  • Amiodarone
  • Astemizole
  • Atazanavir
  • Atorvastatin
  • Bedaquiline
  • Cisapride
  • Citalopram
  • Clarithromycin
  • Clozapine
  • Conivaptan
  • Crizotinib
  • Dabrafenib
  • Dasatinib
  • Dihydroergotamine
  • Disopyramide
  • Dofetilide
  • Domperidone
  • Dronedarone
  • Eletriptan
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Erythromycin
  • Escitalopram
  • Halofantrine
  • Haloperidol
  • Iloperidone
  • Itraconazole
  • Ivabradine
  • Ketoconazole
  • Lapatinib
  • Lomitapide
  • Lopinavir
  • Lovastatin
  • Lumefantrine
  • Lurasidone
  • Maraviroc
  • Mefloquine
  • Mesoridazine
  • Methadone
  • Methylergonovine
  • Methysergide
  • Mifepristone
  • Nilotinib
  • Nimodipine
  • Ondansetron
  • Pazopanib
  • Pimozide
  • Piperaquine
  • Propafenone
  • Quetiapine
  • Quinidine
  • Quinine
  • Ranolazine
  • Rilpivirine
  • Ritonavir
  • Salmeterol
  • Saquinavir
  • Simvastatin
  • Sirolimus
  • Solifenacin
  • Sorafenib
  • Sparfloxacin
  • Sunitinib
  • Tacrolimus
  • Tamoxifen
  • Telithromycin
  • Terfenadine
  • Thioridazine
  • Tolvaptan
  • Toremifene
  • Trazodone
  • Vandetanib
  • Vardenafil
  • Vemurafenib
  • Vilanterol
  • Vinflunine
  • Vorapaxar
  • Voriconazole
  • Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Ado-Trastuzumab Emtansine
  • Amitriptyline
  • Amoxapine
  • Apomorphine
  • Arsenic Trioxide
  • Asenapine
  • Avanafil
  • Axitinib
  • Azithromycin
  • Boceprevir
  • Bosutinib
  • Cabozantinib
  • Ceritinib
  • Chloroquine
  • Chlorpromazine
  • Cimetidine
  • Ciprofloxacin
  • Clomipramine
  • Cyclosporine
  • Desipramine
  • Dolasetron
  • Doxorubicin
  • Doxorubicin Hydrochloride Liposome
  • Droperidol
  • Efavirenz
  • Enzalutamide
  • Esomeprazole
  • Etravirine
  • Everolimus
  • Fentanyl
  • Fingolimod
  • Flecainide
  • Fluconazole
  • Fluoxetine
  • Fluticasone
  • Fosamprenavir
  • Fosphenytoin
  • Gatifloxacin
  • Gemifloxacin
  • Granisetron
  • Hydrocodone
  • Ibrutinib
  • Ibutilide
  • Imipramine
  • Ivacaftor
  • Levofloxacin
  • Levomilnacipran
  • Macitentan
  • Midazolam
  • Moxifloxacin
  • Norfloxacin
  • Nortriptyline
  • Octreotide
  • Ofloxacin
  • Paliperidone
  • Perflutren Lipid Microsphere
  • Phenytoin
  • Pomalidomide
  • Ponatinib
  • Procainamide
  • Prochlorperazine
  • Promethazine
  • Protriptyline
  • Regorafenib
  • Retapamulin
  • Rifabutin
  • Rifampin
  • Rivaroxaban
  • Romidepsin
  • Ruxolitinib
  • Sevoflurane
  • Simeprevir
  • Sodium Phosphate
  • Sodium Phosphate, Dibasic
  • Sodium Phosphate, Monobasic
  • Sotalol
  • Tamsulosin
  • Telaprevir
  • Telavancin
  • Tetrabenazine
  • Tizanidine
  • Tocophersolan
  • Trabectedin
  • Trifluoperazine
  • Trimipramine
  • Vilazodone
  • Vinblastine
  • Vincristine
  • Vincristine Sulfate Liposome
  • Vinorelbine
  • Warfarin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Digoxin
  • Lorazepam
  • Metoclopramide
  • Topiramate

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart disease, history of or
  • Heart rhythm problems (eg, arrhythmia, QT prolongation) or
  • Liver disease or
  • Mineral imbalance (low potassium, magnesium, or calcium in the blood)—These conditions may cause side effects to become worse.
  • Kidney disease, severe—May cause the medicine to not work as well.