Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of PEG-electrolyte solution in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of PEG-electrolyte solution in the elderly. However, elderly patients are more likely to have serious side effects (eg, upper GI bleeding, trouble breathing), which may require caution in patients using this medicine.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Eplerenone
  • Fesoterodine
  • Glycopyrrolate
  • Trospium

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acalabrutinib
  • Alacepril
  • Amiloride
  • Amphetamine
  • Atazanavir
  • Benazepril
  • Benzphetamine
  • Bisacodyl
  • Cabotegravir
  • Canrenoate
  • Captopril
  • Cefuroxime Axetil
  • Cilazapril
  • Delapril
  • Dextroamphetamine
  • Digoxin
  • Erdafitinib
  • Fosinopril
  • Gefitinib
  • Imidapril
  • Indomethacin
  • Infigratinib
  • Ketoconazole
  • Ledipasvir
  • Licorice
  • Lisdexamfetamine
  • Lisinopril
  • Mefenamic Acid
  • Memantine
  • Methamphetamine
  • Moexipril
  • Neratinib
  • Octreotide
  • Pazopanib
  • Pentopril
  • Perindopril
  • Quinapril
  • Ramipril
  • Rilpivirine
  • Selpercatinib
  • Senna
  • Sodium Picosulfate
  • Sotorasib
  • Sparsentan
  • Spirapril
  • Spironolactone
  • Temocapril
  • Trandolapril
  • Triamterene
  • Zofenopril

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Chloroquine
  • Levothyroxine
  • Licorice

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Angina (chest pain), unstable or
  • Heart attack, recent or
  • Heart disease (eg, cardiomyopathy) or
  • Hypocalcemia (low calcium in the blood) or
  • Hypokalemia (low potassium in the blood) or
  • Hypomagnesemia (low magnesium in the blood) or
  • Hyponatremia (low sodium level in the blood) or
  • Withdrawal from alcohol or benzodiazepines (eg, alprazolam, clonazepam, diazepam, lorazepam, Xanax®)—May increase risk for seizures, arrhythmia, or kidney problems.
  • Congestive heart failure or
  • Dehydration or
  • Heart rhythm problems (eg, prolonged QT interval, uncontrolled arrhythmia), history of or
  • Inflammatory bowel disease or
  • Kidney disease or
  • Seizures, history of or
  • Trouble swallowing or
  • Ulcerative colitis, active and severe—Use with caution. May make these conditions worse.
  • Fluid and electrolyte imbalance—Use with caution. These conditions may increase risk for more side effects and must be corrected first before using this medicine.
  • Gastric retention (problems with emptying of food or fluid from the stomach) or
  • Stomach or bowel problems (eg, blockage, ileus, perforation) or
  • Toxic megacolon (a very dilated intestine)—Should not be used in patients with these conditions.