Precautions

Drug information provided by: Micromedex

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during therapy and for 6 months after the last dose of this medicine. If you think you have become pregnant while using the medicine, tell your doctor right away.

You should not receive this medicine if you are also using oxaliplatin and have mutant KRAS metastatic colorectal cancer or if your KRAS tumor status is unknown.

Some patients who use this medicine develop serious skin problems that may lead to infections that can become life-threatening. Tell your doctor right away if you have skin changes such as a skin rash, itchiness, skin redness or swelling, dry, peeling skin or fissures, or fingernail changes while using this medicine.

Tell your doctor right away if you are having shortness of breath, chest tightness, or any type of breathing problem while receiving this medicine.

This medicine may cause a rare but serious type of an allergic reaction called an infusion reaction. This can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a fever, chills, trouble with breathing, chest tightness, swelling in your face or hands, lightheadedness, or if you feel like fainting within a few hours after you receive it.

Check with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after your treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

This medicine may cause severe kidney disease in patients who have severe diarrhea and dehydration. This medicine may also increase your risk of having an electrolyte imbalance (e.g., low magnesium, potassium, or calcium in the blood). Tell your doctor right away if you start having bloating or swelling of the face, arms, hands, lower legs, ankles, or feet, decreased urination, dizziness, headache, lethargy, muscle cramps or twitching, mood or mental changes, nausea, rapid weight gain, or unusual tiredness or weakness while being treated with this medicine.

Avoid overexposing your skin to sunlight. Always use sunscreen or sun blocking lotions and wear protective clothing and hats while you are receiving this medicine and for 2 months after the last dose.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.