Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Bactroban
  2. Centany

Descriptions


Mupirocin is used to treat bacterial infections. It works by killing bacteria or preventing their growth.

Mupirocin ointment is applied to the skin to treat impetigo. It may also be used for other bacterial skin infections as determined by your doctor.

Mupirocin cream is applied to the skin to treat secondarily infected traumatic skin lesions.

Mupirocin is available in the U.S. only with your doctor's prescription.

This product is available in the following dosage forms:

  • Ointment
  • Cream

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Safety and effectiveness of mupirocin cream have not been established in children up to 3 months of age.

Safety and effectiveness of mupirocin ointment have not been established in children up to 2 months of age.

Geriatric

No overall difference in safety and efficacy were observed in patients over 65 years of age.

Pregnancy

Information about this mupirocin-topical-route
Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use

Do not use this medicine in the eyes.

To use:

  • Before applying this medicine, wash the affected area(s) with soap and water, and dry thoroughly. Then apply a small amount to the affected area(s) and rub in gently.
  • After applying this medicine, the treated area(s) may be covered with a gauze dressing if desired.

To help clear up your skin infection completely, keep using mupirocin for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For ointment dosage form:
    • Impetigo:
      • Adults and children 2 months of age and older— Apply three times a day.
      • Children under 2 months of age — Use and dose must be determined by your doctor.
  • For cream dosage form:
    • Secondarily infected traumatic skin lesions
      • Adults and children 3 months of age and older— Apply three times a day, for 10 days.
      • Children under 3 months of age — Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions

If your skin infection does not improve within 3 to 5 days, or if it becomes worse, check with your health care professional.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.