Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Menactra
  2. Menomune-ACYW-135
  3. Menveo
  4. Trumenba

Descriptions


Meningococcal vaccine is an active immunizing agent used to prevent infection by certain groups of meningococcal bacteria. The vaccine works by causing your body to produce its own protection (antibodies) against the disease.

Menomune® is active against groups A, C, Y and W-135 meningococcal bacteria only.

Trumenba® is active against group B meningococcal bacteria only. .

Meningococcal infection can cause life-threatening illnesses, such as meningococcal meningitis, which affects the brain, and meningococcemia, which affects the blood. Some persons with meningococcal meningitis and/or meningococcemia also may die. These diseases are more likely to occur in young children and in persons with certain diseases or conditions that make them more susceptible to a meningococcal infection or more likely to develop serious problems from a meningococcal infection.

Immunization against meningococcal disease is recommended for persons who are at risk of getting the disease because:

  • They have certain diseases or conditions that make them more susceptible to a meningococcal infection or more likely to develop serious problems from a meningococcal infection.
  • They are living in, working in, or visiting an area where there is a strong possibility of contracting meningococcal disease.

Menomune® is recommended for use in patients 2 years of age and older.

Trumenba® is recommended for use in patients 10 to 25 years of age. .

This vaccine is to be given only by or under the supervision of your doctor.

This product is available in the following dosage forms:

  • Powder for Suspension
  • Suspension
  • Kit
  • Powder for Solution
  • Injectable

Before Using

In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of Menomune® in children younger than 2 years of age , however, in some cases children as young as 3 months of age may be vaccinated.

Appropriate studies have not been performed on the relationship of age to the effects of Trumenba® in children younger than 10 years of age.

Geriatric

Appropriate studies have not been performed on the relationship of age to the effects of meningococcal vaccine in adults older than 65 years of age. Safety and efficacy have not been established.

Pregnancy

Information about this meningococcal-vaccine-intramuscular-route-subcutaneous-route
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

Breastfeeding

Breastfeeding

Breastfeeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Breastfeeding

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this vaccine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Measles Virus Vaccine, Live

Receiving this vaccine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Tetanus Toxoid

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Severe illness with fever—The symptoms of the condition may be confused with the possible side effects of the vaccine.

Proper Use

A nurse or other trained health professional will give this vaccine to you or your child.

  • Menomune® vaccine:
    • For prevention of meningococcal meningitis:
      • Adults and children—One dose injected under the skin.
      • Usually a person needs to receive the vaccine only once. However, additional injections may be needed for young children who remain at high risk for meningococcal disease.
  • For Trumenba® vaccine:
    • For prevention of meningococcal meningitis:
      • Patients aged 10 to 25 years: An injection is given into a muscle. Three doses, each given several months apart, are necessary.
      • It is very important for you or your child to receive all of the 3 shots for the vaccine. If you or your child misses a dose, call your or your child’s doctor for another appointment.

Precautions

It is very important that your doctor check you or your child at regular visits to make sure this vaccine is working properly and to check for unwanted effects.

Check with your doctor right away if you have a cough, difficulty with swallowing, dizziness, fast heartbeat, hives, itching, puffiness or swelling of the eyelids or around the eyes, face, lips or tongue, skin rash, tightness in the chest, or unusual tiredness or weakness. These could be symptoms of an allergic reaction to the vaccine.

It is important that your doctor should know about all other vaccines you or your child have recently received, including a flu shot.

This vaccine may not protect everyone who receives it.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Chills

Less common

  1. Fever over 100 degrees F
  2. general feeling of discomfort or illness

Incidence not known

  1. Cough
  2. difficulty with breathing or swallowing
  3. dizziness
  4. fast heartbeat
  5. hives, itching, or skin rash
  6. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  7. reddening of the skin, especially around the ears
  8. unusual tiredness or weakness (sudden and severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Headache
  2. muscle pain
  3. redness, tenderness, soreness, or pain at the injection site

Less common

  1. Hard lump at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.