Proper Use

Drug information provided by: Micromedex

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If you are using this medicine without a prescription, follow the instructions on the medicine label.

Take this medicine before a meal and for the full time of treatment, even if you begin to feel better after a few days.

If you are taking this medicine to treat an ulcer that is associated with an H. pylori infection, take it together with the antibiotics (e.g., amoxicillin, clarithromycin) at the same time of day.

To use the capsule:

  • Swallow the capsule whole. Do not break, crush, or chew it.
  • If the capsule cannot be swallowed, open it and sprinkle the contents on one tablespoonful of applesauce, Ensure® pudding, cottage cheese, yogurt, or strained pears. Swallow the mixture right away. Do not chew or crush the granules.
  • The contents of the capsule can also be mixed with 2 ounces (1/4 cup or 60 mL) of apple juice, orange juice, or tomato juice. After mixing, drink and swallow the mixture right away. Do not chew or crush the granules. Refill the cup 2 more times with juice and drink the liquid to make sure all of the medicine is taken.

To use the capsule with a nasogastric (NG) tube:

  • Open the capsule and mix the contents with 40 mL of apple juice. Do not use any other liquids.
  • Inject or pour the mixture into the nasogastric tube.
  • Flush the tube with more apple juice to rinse all of the medicine from the tube into the stomach.

To use the orally disintegrating tablet:

  • Make sure your hands are dry before you handle the tablet.
  • Do not crush, chew, break, or cut the tablet.
  • Place the tablet on the tongue, with or without water, and allow it to dissolve into particles. Swallow the particles right away.

To use the orally disintegrating tablet with an oral syringe:

  • Make sure your hands are dry before you handle the tablet.
  • Do not crush, break, or cut the tablet.
  • For the 15 mg tablet: Place it in the oral syringe and add 4 mL of water.
  • For the 30 mg tablet: Place it in the oral syringe and add 10 mL of water.
  • Shake the syringe gently until the tablet dissolves and is mixed well.
  • Give the mixture within 15 minutes.
  • Refill the syringe with 2 mL (15 mg tablet) or 5 mL (30 mg tablet) of water and shake it gently. Give the mixture to make sure all of the medicine is taken.

To use the orally disintegrating tablet with a nasogastric (NG) tube:

  • Make sure your hands are dry before you handle the tablet.
  • Do not crush, break, or cut the tablet.
  • For the 15 mg tablet: Place it in the syringe and add 4 mL of water.
  • For the 30 mg tablet: Place it in the syringe and add 10 mL of water.
  • Shake the syringe gently until the tablet dissolves and is mixed well.
  • Inject or pour the mixture into the nasogastric tube within 15 minutes.
  • Refill the syringe with 5 mL of water and shake it gently. Flush the tube with the water to rinse all of the medicine from the tube into the stomach.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage forms (capsules or orally disintegrating tablets):
    • To treat duodenal ulcers:
      • Adults—15 milligrams (mg) once a day before a meal. Your doctor may adjust your dose if needed.
      • Children—Use and dose must be determined by your doctor.
    • To treat duodenal ulcers with H. pylori infection:
      • Adults—30 milligrams (mg) before meals two or three times a day. The dose is usually taken together with amoxicillin or clarithromycin plus amoxicillin. Your doctor may adjust your dose if needed.
      • Children—Use and dose must be determined by your doctor.
    • To treat erosive esophagitis:
      • Adults—15 to 30 milligrams (mg) once a day before a meal. Your doctor may adjust your dose if needed.
      • Teenagers and children 12 years of age—30 mg once a day before a meal. Your doctor may adjust your dose if needed.
      • Children 1 to 11 years of age and weighing over 30 kg—30 mg once a day before a meal. Your doctor may adjust your dose if needed.
      • Children 1 to 11 years of age and weighing 30 kg or less—15 mg once a day before a meal. Your doctor may adjust your dose if needed.
      • Children younger than 1 year of age—Use and dose must be determined by your doctor.
    • To treat gastric ulcers:
      • Adults—15 to 30 milligrams (mg) once a day before a meal. Your doctor may adjust your dose if needed.
      • Children—Use and dose must be determined by your doctor.
    • To treat gastroesophageal reflux disease (GERD):
      • Adults, teenagers, and children 12 years of age—15 milligrams (mg) once a day before a meal. Your doctor may adjust your dose if needed.
      • Children 1 to 11 years of age and weighing over 30 kg—30 mg once a day before a meal. Your doctor may adjust your dose if needed.
      • Children 1 to 11 years of age and weighing 30 kg or less—15 mg once a day before a meal. Your doctor may adjust your dose if needed.
      • Children younger than 1 year of age—Use and dose must be determined by your doctor.
    • To treat Zollinger-Ellison syndrome (ZES):
      • Adults—60 milligrams (mg) once a day before a meal. Your doctor may adjust your dose if needed.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.