Before Using

Drug information provided by: Micromedex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of immune globulin injection in children. However, safety and efficacy have not been established in children with CIDP, safety and efficacy have not been established for Flebogamma®, Gammagard Liquid®, or Gammaplex® to treat MMN, and subcutaneous injection of Gammaked™ or Gamunex®-C in children with PI. Safety and efficacy have not been established for Gammagard Liquid to treat PI, with Hizentra® or Vivaglobin® in children younger than 2 years of age, or use of Gammaplex® in children with PI or ITP.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of immune globulin injection in the elderly. However, elderly patients are more likely to have age-related blood clotting problems, kidney disease, or heart disease, which may require caution for patients receiving immune globulin injection.

Pregnancy

Information about this immune-globulin-intramuscular-route-intravenous-route-subcutaneous-route
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Anemia, history of or
  • Bleeding problems, history of or
  • Hyponatremia (low sodium in the blood) or
  • Kidney problems—Use with caution. May make these conditions worse.
  • Atherosclerosis (hardening of the arteries), history of or
  • Blood clotting problems, history of or
  • Diabetes or
  • Heart attack or stroke, recent or
  • Heart or blood vessel disease or
  • Hyperproteinemia (high protein in the blood) or
  • Hyperviscosity (thick blood), known or suspected or
  • Hypovolemia (low blood volume or major loss of body fluids) or
  • IgA (immunoglobulin A) deficiency with antibodies against IgA or
  • Paraproteinemia (paraproteins in the blood) or
  • Sepsis (serious infection in the body)—Use with caution. May cause side effects to become worse.
  • Hereditary intolerance to fructose or sucrose or
  • IgA (immunoglobulin A) deficiency with antibodies against IgA—Gammaplex® should not be used in patients with these conditions.
  • Hyperprolinemia (too much proline in the blood) or
  • IgA (immunoglobulin A) deficiency with antibodies against IgA—Hizentra® should not be used in patients with these conditions.