Interactions

Interactions with Drugs

Honey may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants ("blood thinners") such as warfarin (Coumadin®) or heparin, anti-platelet drugs such as clopidogrel (Plavix®), and non-steroidal anti-inflammatory drugs such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).

Honey may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. People taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.

Honey may cause low blood pressure. Caution is advised in people taking drugs that lower blood pressure.

Honey may interfere with the way the body processes certain drugs using the liver's "cytochrome P450" enzyme system. As a result, the levels of these drugs may be altered in the blood, and may cause altered effects or potentially serious adverse reactions. People using any medications should check the package insert, and speak with a qualified healthcare professional, including a pharmacist, about possible interactions.

Honey may also interact with agents taken for the blood, agents taken for the heart, agents taken for the nervous system, agents taken for the skin, agents taken for the stomach or intestines, agents taken for the urinary tract, antibiotics, anticancer agents, antifungal agents, anti-inflammatory agents, anti-seizure agents, cholesterol-lowering agents, dental agents, ethanol, weight loss agents, and wound-healing agents.

Interactions with Herbs and Dietary Supplements

Honey may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto. Numerous other agents may theoretically increase the risk of bleeding, although this has not been proven in most cases.

Honey may interfere with the way the body processes certain herbs or supplements using the liver's "cytochrome P450" enzyme system. As a result, the levels of other herbs or supplements may be altered in the blood. It may also alter the effects that other herbs or supplements possibly have on the P450 system.

Honey may lower blood sugar levels. Caution is advised when using herbs or supplements that may also lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.

Honey may cause low blood pressure. Caution is advised in people taking herbs or supplements that lower blood pressure.

Honey may also interact with antibacterials, anticancer herbs and supplements, antifungal herbs and supplements, anti-inflammatory herbs and supplements, antioxidants, anti-seizure herbs and supplements, cholesterol-lowering herbs and supplements, dental herbs and supplements, herbs and supplements taken for the blood, herbs and supplements taken for the heart, herbs and supplements taken for the nervous system, herbs and supplements taken for the skin, herbs and supplements taken for the stomach or intestines, herbs and supplements taken for the urinary tract, weight loss herbs and supplements, and wound-healing herbs and supplements.

This evidence-based monograph was prepared by The Natural Standard Research Collaboration

www.naturalstandard.com