Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Enterex Glutapak-10
  2. Resource Glutasolve
  3. Sympt-X
  4. Sympt-X GI

Descriptions


Glutamine is a substance naturally produced in the body to help regulate cell growth and function. There may also be man-made versions of these substances. Glutamine is used along with human growth hormone and a specialized diet to treat short bowel syndrome

This medicine is available only with your doctor's prescription.

Importance of Diet

For good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods. If you think that you are not getting enough vitamins and/or minerals in your diet, you may choose to take a dietary supplement.

This product is available in the following dosage forms:

  • Powder for Solution
  • Powder for Suspension
  • Tablet
  • Capsule
  • Powder
  • Packet

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of glutamine in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of glutamine in the elderly with use in other age groups. However, elderly patients are more likely to be sensitive requiring the need for dosage adjustment.

Pregnancy

Information about this glutamine-oral-route
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Liver disease—May be worsened by glutamine.

Proper Use

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (powder for oral solution):
    • For short bowel syndrome
      • Adults—30 grams per day in divided doses (5 grams taken 6 times a day) for up to 16 weeks. Taken with meals or snacks, 2 to 3 hours apart while awake.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions

It is very important that your doctor check you at regular visits.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

  1. Blood in urine
  2. changes in skin color
  3. chills
  4. cold hands and feet
  5. confusion
  6. cough
  7. difficulty swallowing
  8. dizziness
  9. fainting
  10. fast heartbeat
  11. fever
  12. frequent and painful urination
  13. headache
  14. hives
  15. itching
  16. lightheadedness
  17. lower back or side pain
  18. pain, redness, or swelling in arm or leg
  19. puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
  20. rapid, shallow breathing
  21. shortness of breath
  22. skin rash
  23. stomach pain
  24. sudden decrease in amount of urine
  25. tightness in chest
  26. unusual tiredness or weakness
  27. wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Cough or hoarseness
  2. frequent urge to defecate
  3. straining while passing stool

Less common

  1. Abnormal or decreased touch sensation
  2. back pain
  3. bacterial infection
  4. bleeding after defecation
  5. bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at site
  6. bloated full feeling
  7. body aches or pain
  8. breast pain, female
  9. chest pain
  10. change in the color, amount, or odor of vaginal discharge
  11. congestion
  12. constipation
  13. Crohn's disease, aggravated
  14. dark urine
  15. decreased urination
  16. diarrhea
  17. difficulty having a bowel movement (stool)
  18. difficulty in moving
  19. discoloration of fingernails or toenails
  20. discouragement
  21. dry mouth
  22. dryness or soreness of throat
  23. ear or hearing symptoms
  24. excess air or gas in stomach or intestines
  25. feeling sad or empty
  26. feeling unusually cold shivering
  27. flatulence
  28. full or bloated feeling
  29. general feeling of discomfort or illness
  30. increase in heart rate
  31. indigestion
  32. irritability
  33. joint pain;
  34. lack of appetite
  35. light-colored stools
  36. loss of appetite
  37. loss of interest or pleasure
  38. muscle aches and pains
  39. muscle pain or stiffness
  40. nausea
  41. pain in joints
  42. pain or burning while urinating
  43. pains in stomach, side, or abdomen, possibly radiating to the back
  44. passing gas
  45. pressure in the stomach
  46. rash
  47. rectal bleeding
  48. runny nose
  49. shivering
  50. sleeplessness
  51. sneezing
  52. sore throat
  53. stomach bloating, burning, cramping, or pain
  54. stuffy nose
  55. sunken eyes
  56. sweating
  57. swelling of abdominal or stomach area
  58. swelling of face
  59. swelling of hands, ankles, feet, or lower legs
  60. swollen joints
  61. tender, swollen glands in neck;
  62. thirst
  63. trouble concentrating
  64. trouble sleeping
  65. trouble in swallowing
  66. unable to sleep
  67. uncomfortable swelling around anus
  68. unpleasant breath odor
  69. unusual tiredness or weakness
  70. voice changes
  71. vomiting
  72. vomiting of blood
  73. weight loss
  74. wrinkled skin
  75. yellow eyes or skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.