Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Furomide MD
  2. Lasix

Descriptions


Furosemide injection is used to help treat fluid retention (edema) and swelling that is caused by congestive heart failure, liver disease (cirrhosis), kidney disease, or other medical conditions.

Furosemide belongs to a group of medicines called loop diuretics or "water pills". It works by acting on the kidneys to increase the flow of urine.

This medicine is to be given only by or under the direct supervision of a doctor.

This product is available in the following dosage forms:

  • Solution
  • Injectable

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of furosemide injection in children. However, premature babies are more likely to have unwanted effects (e.g., kidney stones, hearing problems), which may require caution in patients receiving furosemide injection.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of furosemide injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving furosemide injection.

Pregnancy

Information about this furosemide-injection-route
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amikacin
  • Arsenic Trioxide
  • Bepridil
  • Chloral Hydrate
  • Cisplatin
  • Digitoxin
  • Dofetilide
  • Droperidol
  • Ethacrynic Acid
  • Gentamicin
  • Kanamycin
  • Ketanserin
  • Levomethadyl
  • Lithium
  • Metolazone
  • Neomycin
  • Netilmicin
  • Sotalol
  • Streptomycin
  • Tobramycin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Aceclofenac
  • Acemetacin
  • Alacepril
  • Aliskiren
  • Amtolmetin Guacil
  • Aspirin
  • Benazepril
  • Bromfenac
  • Bufexamac
  • Captopril
  • Celecoxib
  • Cephaloridine
  • Choline Salicylate
  • Cilazapril
  • Clofibrate
  • Clonixin
  • Cyclosporine
  • Delapril
  • Dexibuprofen
  • Dexketoprofen
  • Dibekacin
  • Diclofenac
  • Diflunisal
  • Digoxin
  • Dipyrone
  • Enalaprilat
  • Enalapril Maleate
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Fludrocortisone
  • Flufenamic Acid
  • Flurbiprofen
  • Fosinopril
  • Germanium
  • Ginseng
  • Gossypol
  • Ibuprofen
  • Ibuprofen Lysine
  • Imidapril
  • Indomethacin
  • Ketoprofen
  • Ketorolac
  • Licorice
  • Lisinopril
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Moexipril
  • Morniflumate
  • Nabumetone
  • Naproxen
  • Nepafenac
  • Niflumic Acid
  • Nimesulide
  • Oxaprozin
  • Oxyphenbutazone
  • Pancuronium
  • Parecoxib
  • Pentopril
  • Perindopril
  • Phenylbutazone
  • Piketoprofen
  • Piroxicam
  • Pranoprofen
  • Proglumetacin
  • Propyphenazone
  • Proquazone
  • Quinapril
  • Ramipril
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Sodium Salicylate
  • Spirapril
  • Sulindac
  • Temocapril
  • Tenoxicam
  • Tiaprofenic Acid
  • Tolfenamic Acid
  • Tolmetin
  • Trandolapril
  • Tubocurarine
  • Valdecoxib
  • Vecuronium
  • Zofenopril

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Allergy to sulfa drugs (such as sulfamethoxazole, sulfasalazine, sulfisoxazole, Azulfidine®, Bactrim®, Gantrisin®, or Septra®) or
  • Bladder problem with urinating or
  • Blood or bone marrow problems or
  • Dehydration or
  • Electrolyte imbalance (e.g., low sodium, calcium, magnesium, or potassium in the blood) or
  • Enlarged prostate or
  • Gout or
  • Hearing problems or
  • Hyperuricemia (high uric acid in the blood) or
  • Hypovolemia (low blood volume) or
  • Liver disease, severe (e.g., cirrhosis, hepatic coma) or
  • Systemic lupus erythematosus (SLE) or
  • Tinnitus (ringing in the ears) or
  • Trouble urinating—Use with caution. May make these conditions worse.
  • Anuria (not able to pass urine)—Should not be used in patients with this condition.
  • Diabetes—This medicine may increase the amount of sugar in the blood.
  • Hypertension (high blood pressure)—Your dose of antihypertensive medicines may need to be adjusted to prevent your blood pressure from falling too low.
  • Hypoproteinemia (low protein in the blood) from a kidney problem or
  • Radiocontrast nephropathy (kidney problem), history of—May cause side effects to become worse.
  • Kidney disease, severe—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use

A nurse or other trained health professional will give you or your child this medicine in a hospital. This medicine is given as a shot into a muscle or a vein.

Your doctor will give you a few doses of this medicine until your condition improves, and then switch you or your child to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Precautions

It is very important that your doctor check you or your child closely while you are receiving this medicine. This is to make sure this medicine is working properly. Blood or urine tests may be needed to check for unwanted effects.

Using this medicine while you are pregnant may cause your unborn baby to be bigger than normal. If you think you have become pregnant while using this medicine, tell your doctor right away.

This medicine may cause you or your child to lose more potassium from your body than normal (hypokalemia). This is more likely to occur if you have liver disease (e.g., cirrhosis), or if you are using this medicine together with steroids (cortisone-like medicines), adrenocorticotropic hormone (ACTH), large amounts of licorice, or laxatives for a long time. Tell your doctor if you become sick with severe or continuing nausea, vomiting, or diarrhea, and drink fluids to prevent getting dehydrated. Check with your doctor right away if you have one or more of these symptoms: dry mouth; increased thirst; muscle cramps; or nausea or vomiting.

Stop using this medicine and check with your doctor right away if you or your child have a sudden decrease in hearing or loss of hearing. You may also have dizziness or ringing in the ears with the hearing problem. Tell your doctor if you have dizziness or lightheadedness; a feeling of constant movement of self or surroundings; or a sensation of spinning.

Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, check with your doctor.

This medicine may cause an increase in blood sugar levels. If you or your child are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.

This medicine may make your skin more sensitive to sunlight. Use a sunscreen, hat, and protective clothing when you are outdoors. Avoid sunlamps and tanning beds.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Do not take other medicines unless they have been discussed with your doctor. This especially includes prescription or nonprescription (over-the-counter) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Rare

  1. Chest pain
  2. chills
  3. cough or hoarseness
  4. fever
  5. general feeling of tiredness or weakness
  6. headache
  7. lower back or side pain
  8. painful or difficult urination
  9. shortness of breath
  10. sore throat
  11. sores, ulcers, or white spots on the lips or in the mouth
  12. swollen or painful glands
  13. tightness in the chest
  14. unusual bleeding or bruising
  15. unusual tiredness or weakness
  16. wheezing

Incidence not known

  1. Back or leg pains
  2. black, tarry stools
  3. bladder spasm
  4. bleeding gums
  5. blistering, peeling, or loosening of the skin
  6. bloody or cloudy urine
  7. blurred vision
  8. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  9. clay-colored stools
  10. cold sweats
  11. confusion
  12. constipation
  13. continuing ringing or buzzing or other unexplained noise in the ears
  14. coughing up blood
  15. diarrhea
  16. dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
  17. dry mouth
  18. fast heartbeat
  19. fever with or without chills
  20. flushed, dry skin
  21. fruit-like breath odor
  22. hearing loss
  23. increased hunger or thirst
  24. increased or decreased urination
  25. indigestion
  26. itching
  27. joint stiffness or swelling
  28. loss of appetite
  29. nausea or vomiting
  30. nosebleeds
  31. pain where a shot was given
  32. pains in the stomach, side, or abdomen, possibly radiating to the back
  33. pale skin
  34. pinpoint red spots on the skin
  35. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  36. red, irritated eyes
  37. scaly skin
  38. skin rash
  39. sweating
  40. swelling of the feet or lower legs
  41. troubled breathing with exertion
  42. unpleasant breath odor
  43. unusual weight loss
  44. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  1. Feeling of constant movement of self or surroundings
  2. hives or welts
  3. increased sensitivity of the skin to sunlight
  4. muscle spasm
  5. redness or other discoloration of the skin
  6. restlessness
  7. sensation of spinning
  8. severe sunburn
  9. weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.