Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not stop taking this medicine without first checking with your doctor. When your supply of this medicine is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of this medicine.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Fosamprenavir oral suspension should be taken by adults without food. Children should take the oral suspension with food.

Shake the oral suspension well before each use. Use a marked measuring spoon, oral syringe, or medicine cup to measure the dose. The average household teaspoon may not hold the right amount of liquid.

Fosamprenavir tablets may be taken with or without food. However, it should not be taken with a high-fat meal. Taking fosamprenavir with a high-fat meal may decrease the amount of fosamprenavir that is absorbed by the body and prevent the medicine from working properly.

It is important to take fosamprenavir as part of a combination treatment. Your dose of medicine will be based on what other medicines you are taking, as well as your weight. Be sure to take all the medicines your doctor has prescribed for you, including fosamprenavir.

Keep using fosamprenavir for the full time of treatment, even if you begin to feel better. If you stop the medicine even briefly, the virus may become harder to treat.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times, day and night. For example, if you are to take two doses a day, the doses should be spaced about 12 hours apart. If you need help in planning the best times to take your medicine, check with your doctor.

Only take medicine that your doctor has prescribed especially for you. Do not share your medicine with others.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage forms (suspension or tablets):
    • For treatment of HIV infection:
      • Adults who have not taken HIV medicines called protease inhibitors in the past (fosamprenavir alone)—1400 milligrams (mg) (2 tablets) 2 times a day.
      • Adults who have not taken HIV medicines called protease inhibitors in the past (fosamprenavir together with ritonavir)—1400 mg (2 tablets) fosamprenavir with 200 mg ritonavir once a day or 1400 mg (2 tablets) fosamprenavir with 100 mg ritonavir once a day or 700 mg fosamprenavir with 100 mg ritonavir 2 times a day.
      • Adults who have taken HIV medicines called protease inhibitors in the past (fosamprenavir together with ritonavir)—700 mg fosamprenavir with 100 mg ritonavir 2 times a day. Adults who have taken protease inhibitors in the past should not take the combination of fosamprenavir with ritonavir only once a day. Check with your doctor if you are unsure of what amounts and how many times a day you should be taking your medicines. If you are taking fosamprenavir with ritonavir and efavirenz, check with your doctor for the correct doses.
      • Children 4 weeks of age and older (fosamprenavir together with ritonavir)—Dose is based on body weight and must be determined by your doctor. The usual fosamprenavir suspension dose for patients weighing 20 kilograms (kg) or more is 18 milligrams (mg) per kilogram (kg) of body weight 2 times a day with ritonavir 3 mg per kg 2 times per day. Fosamprenavir doses up to 45 mg per kg 2 times per day with ritonavir 7 mg/kg 2 times a day are used for patients weighing less than 11 kg. However, the dose is usually not more than fosamprenavir 700 mg with ritonavir 100 mg 2 times a day.
      • Children 2 years of age and older who have not taken HIV medicines called protease inhibitors in the past (fosamprenavir alone)—Dose is based on body weight and must be determined by your doctor. The usual suspension dose is 30 mg per kg of body weight 2 times a day. Doses up to 1400 mg (2 tablets) 2 times a day may be used for children weighing 47 kg or more.
      • Children 4 weeks of age and older—Using fosamprenavir once a day is not recommended for children. Fosamprenavir should always be given twice daily unless otherwise determined by your doctor.
      • Children younger than 4 weeks of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you or your child vomits 30 minutes after the first dose, a second dose should be taken right away.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

The oral suspension may also be refrigerated. Do not freeze.