Interactions with Drugs
Folate may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. People taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.
Folate may cause low blood pressure. Caution is advised in people taking drugs that lower blood pressure.
Folate may also interact with agents that promote urination, alcohol, Alzheimer's agents, aminosalicylic acid, antacids, antibiotics, anticancer agents, antidepressants, anti-malaria agents, anti-seizure agents, aspirin, birth control, cholestyramine, colestipol, conjugated estrogens, cycloserine, folic acid antagonists, H2 blockers, heart agents, homocysteine-lowering agents, iron, methotrexate, methylprednisolone sodium succinate (Solu-Medrol®), nervous system agents, nitroglycerin, nonsteroidal anti-inflammatories (NSAIDs), omega-3 fatty acids, pancreatic extracts, pemetrexed disodium, pentamidine, phenytoin, proton pump inhibitors, sulfasalazine, sulfonamides, tobacco, trimethoprim, vitamin A, vitamin B12, warfarin, and zinc.
Interactions with Herbs and Dietary Supplements
Folate may lower blood sugar levels. Caution is advised when using herbs or supplements that may also lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.
Folate may cause low blood pressure. Caution is advised in people taking herbs or supplements that lower blood pressure.
Folate may also interact with aged garlic extract, alcohol, Alzheimer's herbs and supplements, antacids, antibacterials, anticancer herbs and supplements, antidepressants, anti-inflammatories, anti-malaria herbs and supplements, antioxidants, anti-seizure herbs and supplements, B vitamins, birth control, green tea, heart herbs and supplements, herbs and supplements that promote urination, homocysteine-lowering herbs and supplements, iron, leaf concentrate, multiple micronutrients, nervous system herbs and supplements, omega-3 fatty acids, pancreatic extracts, phytoestrogens, probiotics, salicylates, vitamin A, vitamin B12, and zinc.
This evidence-based monograph was prepared by The Natural Standard Research Collaboration