Side Effects

Drug information provided by: Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Black, tarry stools
  2. bleeding gums
  3. blood in the urine or stools
  4. chest pain
  5. chills
  6. cough
  7. fever
  8. painful or difficult urination
  9. pale skin
  10. pinpoint red spots on the skin
  11. shortness of breath
  12. sore throat
  13. sores, ulcers, or white spots on the lips or in the mouth
  14. swollen glands
  15. troubled breathing with exertion
  16. unusual bleeding or bruising
  17. unusual tiredness or weakness

Less common

  1. Blurred vision
  2. confusion
  3. cough or hoarseness, accompanied by fever or chills
  4. difficulty with swallowing
  5. dizziness
  6. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  7. face is warm or hot to touch
  8. fast heartbeat
  9. headache
  10. hives
  11. itching
  12. lower back or side pain, accompanied by fever or chills
  13. nervousness
  14. numbness or tingling in the fingers or toes
  15. pain or redness at the site of injection
  16. pale skin at the site of injection
  17. pounding in the ears
  18. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  19. redness to face
  20. skin rash
  21. slow or fast heartbeat
  22. sweating
  23. tightness in the chest
  24. wheezing


  1. Back pain
  2. difficulty with walking
  3. loss of consciousness
  4. swelling of the face or tongue
  5. tightness in the throat

Incidence not known

  1. Abdominal or stomach pain, severe
  2. blindness
  3. blistering, peeling, or loosening of the skin
  4. blue-yellow color blindness
  5. dark urine
  6. decreased vision
  7. difficult with breathing
  8. eye pain
  9. joint or muscle pain
  10. loss of appetite
  11. nausea or vomiting
  12. red, irritated eyes
  13. red skin lesions, often with a purple center
  14. seizures
  15. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Bad, unusual, or unpleasant (after) taste
  2. change in taste
  3. constipation
  4. cracked lips
  5. hair loss or thinning of the hair
  6. lack or loss of strength
  7. swelling or inflammation of the mouth
  8. weight loss

This medicine often causes a temporary loss of hair. After treatment with etoposide has ended, normal hair growth should return.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.