Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Burning, itching, redness, skin rash, swelling, or soreness at the application site
  2. itching skin

Less common

  1. Blood in the urine
  2. chest pain or tightness
  3. cough
  4. dry, itching, or burning eyes
  5. eye pain
  6. headaches, including migraines
  7. increased sensitivity of the skin to sunlight
  8. pain or tenderness around the eyes and cheekbones
  9. redness of the skin
  10. redness or swelling of the eyes
  11. runny or stuffy nose
  12. skin rash other than at the application site
  13. sore throat
  14. trouble breathing
  15. ulcers or sores on the skin, other than at the application site

Incidence not known

  1. Black, tarry stools
  2. chills
  3. fever
  4. painful or difficult urination
  5. sores, ulcers, or white spots on lips or in mouth
  6. unusual bleeding or bruising
  7. unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Diarrhea
  2. general feeling of discomfort or illness
  3. joint pain
  4. loss of appetite
  5. muscle aches and pains
  6. nausea
  7. scaly, thick, or tingling skin
  8. shivering
  9. sweating
  10. trouble sleeping
  11. vomiting

Less common

  1. Acne
  2. back pain
  3. belching
  4. bleeding skin
  5. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  6. dizziness
  7. heartburn
  8. increase in body movements
  9. indigestion
  10. lack or loss of strength
  11. loss of or change in taste
  12. loss or thinning of the hair
  13. neck pain
  14. sleepiness or unusual drowsiness
  15. stomach upset or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

From Mayo Clinic to your inbox

Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview.

To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail.