Precautions

Drug information provided by: Merative, Micromedex®

It is very important that your doctor check your or your child's progress closely during treatment to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Colistimethate injection may cause some people to become dizzy or to have numbness and tingling sensations in the hands, toes, and feet. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or do not have normal feelings in your hands and feet. If these symptoms are especially bothersome, check with your doctor.

Serious lung or breathing problems may occur after you get a shot of this medicine into one of your muscles. Call your doctor right away if you or your child have any change in your breathing after you receive this medicine.

Colistimethate injection may cause diarrhea, and in some cases it can be severe. It may occur 2 months or more after you stop using this medicine. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues, or gets worse, check with your doctor.

Check with your doctor right away if you or your child has bloody urine, decrease in frequency or amount of urine, increase in blood pressure, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, trouble breathing, unusual tiredness or weakness, vomiting, or weight gain. These could be symptoms of a serious kidney problem.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.