Interactions

Interactions with Drugs

Chondroitin may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants ("blood thinners") such as warfarin (Coumadin®) or heparin, anti-platelet drugs such as clopidogrel (Plavix®), and non-steroidal anti-inflammatory drugs such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).

Chondroitin may affect blood pressure. Caution is advised in people taking drugs that may also affect blood pressure.

Chondroitin may also interact with agents that may affect the immune system, agents that may affect the nervous system, agents that may dissolve easily in water, agents that may harm the liver, agents that may increase sun sensitivity, agents that may treat arthritis, agents that may treat asthma, agents that may treat malaria, agents that may treat osteoporosis, anticancer agents, anti-inflammatory agents, antiviral agents, birth control, calcium salts, cholesterol-lowering agents, diabetes agents, eye agents, gout agents, heart agents, hyaluronan, hyaluronidase, iron salts, non-steroidal anti-inflammatory agents (NSAIDs), polyethylene glycol, skin agents, and stomach agents.

Interactions with Herbs and Dietary Supplements

Chondroitin may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto. Numerous other agents may theoretically increase the risk of bleeding, although this has not been proven in most cases.

Chondroitin may affect blood pressure. Caution is advised in people taking herbs or supplements that affect blood pressure.

Chondroitin may also interact with anticancer herbs and supplements, anti-inflammatory herbs and supplements, antioxidants, antiviral herbs and supplements, avocado, birth control, calcium, camphor, cholesterol-lowering herbs and supplements, fish oil, glucosamine, herbs and supplements that may affect the immune system, herbs and supplements that may affect the nervous system, herbs and supplements that may dissolve easily in water, herbs and supplements that may harm the liver, herbs and supplements that may increase sun sensitivity, herbs and supplements that may promote wound healing, herbs and supplements that may treat arthritis, herbs and supplements that may treat asthma, herbs and supplements that may treat diabetes, herbs and supplements that may treat gout, herbs and supplements that may treat heart disorders, herbs and supplements that may treat malaria, herbs and supplements that may treat osteoporosis, herbs and supplements that may treat stomach disorders, iron, peppermint oil, shark cartilage, and soybean.

This evidence-based monograph was prepared by The Natural Standard Research Collaboration

www.naturalstandard.com