Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Vantin

Descriptions


Cefpodoxime is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Powder for Suspension
  • Tablet

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of cefpodoxime in children. However, safety and efficacy have not been established in infants younger than 2 months of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cefpodoxime in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cefpodoxime.

Pregnancy

Information about this cefpodoxime-oral-route
Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Cimetidine
  • Famotidine
  • Nizatidine
  • Probenecid
  • Ranitidine

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Colitis (inflammation in gut), history of or
  • Diarrhea, severe, history of—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.

Proper Use

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

You or your child must take the tablets with food, while the oral liquid may be taken with or without food.

Shake the oral liquid well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage forms (suspension or tablets):
    • For bronchitis:
      • Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours.
      • Children younger than 12 years of age—Use and dose must be determined by your doctor.
    • For ear infections:
      • Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight every 12 hours.
      • Infants younger than 2 months of age—Use and dose must be determined by your doctor.
    • For gonorrhea:
      • Adults and teenagers 12 years of age and older—200 milligrams (mg) taken as a single dose.
      • Children younger than 12 years of age—Use and dose must be determined by your doctor.
    • For pneumonia:
      • Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours.
      • Children younger than 12 years of age—Use and dose must be determined by your doctor.
    • For sinusitis:
      • Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours.
      • Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight every 12 hours.
      • Infants younger than 2 months of age—Use and dose must be determined by your doctor.
    • For skin infections:
      • Adults and teenagers 12 years of age and older—400 milligrams (mg) every 12 hours.
      • Children younger than 12 years of age—Use and dose must be determined by your doctor.
    • For sore throat and tonsillitis:
      • Adults and teenagers 12 years of age and older—100 milligrams (mg) every 12 hours.
      • Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight every 12 hours.
      • Infants younger than 2 months of age—Use and dose must be determined by your doctor.
    • For urinary tract infections:
      • Adults and teenagers 12 years of age and older—100 milligrams (mg) every 12 hours.
      • Children younger than 12 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the tablets in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the oral liquid in the refrigerator. Throw away any unused medicine after 14 days.

Precautions

If your symptoms or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.

Cefpodoxime may cause diarrhea, and in some cases it can be severe. Do not take any medicine or give medicine to your child to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Before you or your child have any medical tests, tell the medical doctor in charge that you are using this medicine. The results of some tests may be affected by this medicine.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Diarrhea
  2. loose stools

Less common

  1. Change in the color, amount, or odor of vaginal discharge

Rare

  1. Abdominal or stomach cramps or tenderness
  2. black, tarry stools
  3. bladder pain
  4. bleeding gums
  5. bloating or swelling of the face, arms, hands, lower legs, or feet
  6. bloody nose
  7. bloody or cloudy urine
  8. blurred vision
  9. burning while urinating
  10. chest pain
  11. collection of blood under the skin
  12. confusion
  13. continuing ringing or buzzing or other unexplained noise in the ears
  14. cough or hoarseness
  15. cough producing mucus
  16. dark urine
  17. decreased urination
  18. decreased urine output
  19. deep, dark purple bruise
  20. diarrhea, watery and severe, which may also be bloody
  21. difficult or labored breathing
  22. difficult, burning, or painful urination
  23. difficulty with breathing or troubled breathing
  24. dilated neck veins
  25. dizziness
  26. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  27. dry mouth
  28. extreme fatigue
  29. fainting
  30. fast, irregular, pounding, or racing heartbeat or pulse
  31. feeling of warmth or heat
  32. fever or chills
  33. flushing or redness of the skin, especially on the face and neck
  34. frequent urge to urinate
  35. general body swelling
  36. headache
  37. hearing loss
  38. heavier menstrual periods
  39. increase in heart rate
  40. increased thirst
  41. increased urge to urinate during the night
  42. increased weight
  43. irregular breathing
  44. irregular heartbeat
  45. itching of the vagina or genital area
  46. itching, pain, redness, or swelling
  47. loss of appetite
  48. lower back or side pain
  49. nausea or vomiting
  50. nervousness
  51. noisy breathing
  52. nosebleeds
  53. pain
  54. pain during sexual intercourse
  55. pain or swelling of the treated skin
  56. pain or tenderness around the eyes and cheekbones
  57. pain, warmth, or burning in the fingers, toes, and legs
  58. pale skin
  59. pinpoint red spots on the skin
  60. pounding in the ears
  61. problems with vision or hearing
  62. rapid breathing
  63. rapid weight gain
  64. runny nose
  65. shortness of breath or troubled breathing
  66. skin rash
  67. slow or fast heartbeat
  68. sneezing
  69. sore throat
  70. sores, ulcers, or white spots on the lips or in the mouth
  71. stuffy or runny nose
  72. sunken eyes
  73. sweating
  74. swelling of the face, fingers, feet, or lower legs
  75. swelling or puffiness of the face
  76. swollen glands
  77. thick, white vaginal discharge with no odor or with a mild odor
  78. thirst
  79. tightness of the chest or wheezing
  80. tingling of the hands or feet
  81. troubled breathing
  82. troubled breathing with exertion
  83. unusual bleeding or bruising
  84. unusual tiredness or weakness
  85. unusual weight gain or loss
  86. waking to urinate at night
  87. weight gain
  88. wheezing
  89. wrinkled skin
  90. yellowing of the eyes or skin

Incidence not known

  1. Abdominal or stomach pain
  2. blistering, peeling, or loosening of the skin
  3. bloody, black, or tarry stools
  4. clay-colored stools
  5. feeling of discomfort
  6. fever with or without chills
  7. general feeling of tiredness or weakness
  8. high fever
  9. inflammation of the joints
  10. irritation or inflammation of the eyelid
  11. itching
  12. joint or muscle pain
  13. muscle aches
  14. rectal bleeding
  15. red skin lesions, often with a purple center
  16. red, irritated eyes
  17. seizures
  18. sudden decrease in the amount of urine
  19. swollen lymph glands
  20. swollen or painful glands
  21. unpleasant breath odor
  22. vomiting of blood

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

  1. Accumulation of pus
  2. acid or sour stomach
  3. ankle, knee, or great toe joint pain
  4. bad, unusual, or unpleasant (after) taste
  5. belching
  6. blemishes on the skin
  7. bloated or full feeling
  8. burning feeling in the chest or stomach
  9. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  10. change in taste
  11. constipation
  12. cracks in the skin
  13. decreased appetite
  14. difficulty with moving
  15. dry skin
  16. excess air or gas in the stomach or intestines
  17. fear or nervousness
  18. feeling of constant movement of self or surroundings
  19. frequent urge to defecate
  20. general feeling of discomfort or illness
  21. hair loss
  22. headache, severe and throbbing
  23. heartburn
  24. hives or welts
  25. increase in body movements
  26. increased sweating
  27. increased thirst
  28. indigestion
  29. irritation or soreness of the mouth
  30. joint stiffness or swelling
  31. lack or loss of strength
  32. loss of heat from the body
  33. lower back or side pain
  34. muscle aching or cramping
  35. muscle pains or stiffness
  36. passing of gas
  37. peeling of the skin
  38. pimples
  39. poor concentration
  40. pressure in the stomach
  41. red, sore eyes
  42. red, swollen skin
  43. redness of the skin
  44. scaly skin
  45. seeing, hearing, or feeling things that are not there
  46. sensation of spinning
  47. sleepiness or unusual drowsiness
  48. sleeplessness
  49. sore mouth or tongue
  50. soreness or redness around the fingernails and toenails
  51. stomach discomfort, upset, or pain
  52. stomach upset
  53. straining while passing stool
  54. swelling of the abdominal or stomach area
  55. swelling or inflammation of the mouth
  56. swollen, red, or tender area of infection
  57. trouble with sleeping
  58. unable to sleep
  59. white patches in the mouth, tongue, or throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.