Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Cefotan

Descriptions


Cefotetan injection is used to treat bacterial infections in many different parts of the body. This medicine is also given before certain types of surgery to prevent infections.

Cefotetan injection belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Powder for Solution

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of cefotetan injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cefotetan injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cefotetan injection.

Pregnancy

Information about this cefotetan-injection-route
Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Colitis (inflammation in gut), history of or
  • Diarrhea, severe, history of or
  • Hemolytic anemia or
  • Seizures—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.

Proper Use

A nurse or other trained health professional will give you this medicine. This medicine is given as a shot into one of your muscles, or through a needle placed in one of your veins.

Precautions

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Hemolytic anemia may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you have back, leg, or stomach pains; bleeding gums; chills; dark urine; difficulty with breathing; fever; general body swelling; headache; loss of appetite; nausea or vomiting; nosebleeds; pale skin; sore throat; unusual tiredness or weakness; or yellowing of the eyes or skin.

Cefotetan injection may cause diarrhea, and in some cases it can be severe. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Do not drink alcohol while you are receiving cefotetan injection and for 3 days (72 hours) after your last dose. Drinking alcohol during this period may cause flushing; headache; sweating; and fast, pounding, or irregular heartbeat.

Before you have any medical tests, tell the medical doctor in charge that you are receiving this medicine. The results of some tests may be affected by this medicine.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common

  1. Abdominal or stomach cramps or tenderness
  2. back, leg, or stomach pains
  3. black, tarry stools
  4. bleeding gums
  5. bloating
  6. chest pain
  7. chills
  8. cough
  9. dark urine
  10. diarrhea
  11. diarrhea, watery and severe, which may also be bloody
  12. difficulty with breathing
  13. fever
  14. general body swelling
  15. headache
  16. increased thirst
  17. loss of appetite
  18. nausea or vomiting
  19. nosebleeds
  20. pain
  21. painful or difficult urination
  22. pale skin
  23. shortness of breath
  24. sore throat
  25. sores, ulcers, or white spots on the lips or in the mouth
  26. swollen glands
  27. unusual bleeding or bruising
  28. unusual tiredness or weakness
  29. unusual weight loss
  30. yellowing of the eyes or skin

Rare

  1. Blood in the urine
  2. bluish color
  3. change in frequency of urination or amount of urine
  4. changes in skin color
  5. drowsiness
  6. increased thirst
  7. swelling of the feet or lower legs
  8. tenderness
  9. weakness

Incidence not known

  1. Blistering, peeling, or loosening of the skin
  2. cough or hoarseness
  3. coughing up blood
  4. difficulty with swallowing
  5. dizziness
  6. fast heartbeat
  7. fever with or without chills
  8. general feeling of tiredness or weakness
  9. high fever
  10. increased menstrual flow or vaginal bleeding
  11. itching
  12. itching of the vagina or genital area
  13. joint or muscle pain
  14. lower back or side pain
  15. nosebleeds
  16. pain during sexual intercourse
  17. paralysis
  18. pinpoint red spots on the skin
  19. prolonged bleeding from cuts
  20. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  21. rash
  22. red or black, tarry stools
  23. red or dark brown urine
  24. red skin lesions, often with a purple center
  25. red, irritated eyes
  26. seizures
  27. skin rash
  28. sudden decrease in the amount of urine
  29. swollen or painful glands
  30. thick, white vaginal discharge with no odor or with a mild odor
  31. tightness in the chest
  32. unpleasant breath odor
  33. vomiting of blood
  34. wheezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.