Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of bromocriptine to treat acromegaly, Parkinson's disease, and type 2 diabetes in the pediatric population. Safety and efficacy have not been established.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of bromocriptine in children 16 years of age and older with prolactin-secreting pituitary adenomas. However, safety and efficacy have not been established in children younger than 16 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of bromocriptine in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults and are more likely to have confusion, hallucinations, or uncontrolled body movements, and age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving bromocriptine.

Breastfeeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Atazanavir
  • Cobicistat
  • Darunavir
  • Eletriptan
  • Frovatriptan
  • Itraconazole
  • Letermovir
  • Naratriptan
  • Nirmatrelvir
  • Rizatriptan
  • Sulpiride
  • Sumatriptan
  • Zolmitriptan

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Abametapir
  • Almotriptan
  • Amoxapine
  • Boceprevir
  • Carbamazepine
  • Ceritinib
  • Chlorothiazide
  • Chlorthalidone
  • Clarithromycin
  • Clomipramine
  • Conivaptan
  • Dihydroergotamine
  • Fedratinib
  • Fexinidazole
  • Fosnetupitant
  • Furosemide
  • Haloperidol
  • Hydrochlorothiazide
  • Hydroflumethiazide
  • Idelalisib
  • Indapamide
  • Indinavir
  • Insulin
  • Insulin Aspart, Recombinant
  • Insulin Bovine
  • Insulin Degludec
  • Insulin Detemir
  • Insulin Glargine, Recombinant
  • Insulin Glulisine
  • Insulin Lispro, Recombinant
  • Isometheptene
  • Ketoconazole
  • Lopinavir
  • Mavacamten
  • Metoclopramide
  • Metolazone
  • Nefazodone
  • Nelfinavir
  • Netupitant
  • Olanzapine
  • Phenobarbital
  • Phenylpropanolamine
  • Polythiazide
  • Posaconazole
  • Pramlintide
  • Primidone
  • Propatyl Nitrate
  • Risperidone
  • Ritonavir
  • Saquinavir
  • Telaprevir
  • Telithromycin
  • Thioctic Acid
  • Triamterene
  • Voriconazole

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Bromperidol
  • Cyclosporine
  • Kava
  • Thioridazine

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Coronary artery disease or other serious heart or blood vessel disorder, history of or
  • Hypertension (high blood pressure), uncontrolled or
  • Pregnancy-induced high blood pressure—Parlodel® should not be used in patients with these conditions unless medically necessary.
  • Diabetic ketoacidosis (ketones in the blood) or
  • Syncopal (fainting) migraine headaches or
  • Type I diabetes or
  • Postpartum patients (women who had recently given birth)—Cycloset® should not be used in patients with these conditions.
  • Fever or
  • Infection or
  • Surgery or
  • Trauma—These conditions may cause temporary problems with blood sugar control and your doctor may want to treat you temporarily with insulin.
  • Galactose intolerance (a rare genetic disorder) or
  • Glucose-galactose malabsorption (a rare genetic disorder) or
  • Lactase deficiency (a rare genetic disorder), severe—Use of Parlodel® is not recommended in patients with these conditions.
  • Heart attack, history of or
  • Heart or blood vessel disease (eg, pericardial effusion) or
  • Heart rhythm problems or
  • Hypertension (high blood pressure) or
  • Hypotension (low blood pressure) or
  • Lung disease (eg, pleural effusion, pulmonary fibrosis) or
  • Mental illness (eg, psychosis, dementia), history of or
  • Retroperitoneal fibrosis or
  • Seizures, history of or
  • Stomach ulcers or bleeding, or history of or
  • Stroke, history of—Use with caution. May make these conditions worse.
  • Kidney disease or
  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.