Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Amicar

Descriptions


Aminocaproic acid is an antifibrinolytic agent. It is used to treat serious bleeding conditions, especially when the bleeding occurs after dental surgery or other kinds of surgery. This medicine is also sometimes given before an operation to prevent serious bleeding for patients with medical problems that increase the chance of bleeding.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Solution
  • Syrup
  • Tablet

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of aminocaproic acid in the pediatric population. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of aminocaproic acid in geriatric patients.

Pregnancy

Information about this aminocaproic-acid-oral-route
Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Anti-Inhibitor Coagulant Complex
  • Tretinoin

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Blood clots, active or
  • Disseminated intravascular coagulation or DIC (blood clotting problem)—Should not be used in patients with these conditions.
  • Blood clots, history of or
  • Hematuria (blood in the urine)—Use with caution. May make these conditions worse.
  • Kidney disease—The effects of this medicine may be increased because of slower removal of the medicine from the body.

Proper Use

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Measure the oral solution with a marked measuring spoon, oral syringe, or medicine cup.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • To treat bleeding problems:
    • For oral dosage form (solution or tablets):
      • Adults—5 grams (g) or 4 teaspoonfuls as a single dose for the first hour, followed by 1 g or 1 teaspoonful every hour for 8 hours or until bleeding has been controlled.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions

It is very important that your doctor check your progress while you are using this medicine. Blood tests may be needed to see if the medicine is working properly and to check for unwanted effects.

Using this medicine for a long time may cause muscle problems and serious kidney disease. Check with your doctor right away if you have a dark-colored urine; fever; joint pain; muscle cramps or spasms; or unusual tiredness or weakness.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

  1. Anxiety
  2. black, tarry stools
  3. bleeding gums
  4. blood in the urine or stools
  5. blurred vision
  6. change in the ability to see colors, especially blue or yellow
  7. chest pain or discomfort
  8. chills
  9. confusion
  10. cough or hoarseness
  11. dark-colored urine
  12. decreased frequency or amount of urine
  13. difficult or labored breathing
  14. difficulty with moving
  15. difficulty with speaking
  16. difficulty with swallowing
  17. dizziness or lightheadedness
  18. dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  19. double vision
  20. fainting
  21. fast heartbeat
  22. fever with or without chills
  23. general feeling of discomfort or illness
  24. general feeling of tiredness or weakness
  25. headache
  26. hives
  27. inability to move the arms, legs, or facial muscles
  28. inability to speak
  29. increased thirst
  30. itching of the skin
  31. joint pain
  32. loss of appetite
  33. lower back or side pain
  34. muscle aching or cramping
  35. muscle cramps or spasms
  36. muscle pain or stiffness
  37. muscular pain, tenderness, wasting, or weakness
  38. nausea and vomiting
  39. numbness and tingling of the face, fingers, or toes
  40. pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion
  41. painful or difficult urination
  42. pale, bluish-colored, or cold hands or feet
  43. pinpoint red spots on the skin
  44. problems with bleeding or clotting
  45. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  46. shortness of breath
  47. skin rash
  48. slow or irregular heartbeat
  49. slow speech
  50. sore throat
  51. sores, ulcers, or white spots on the lips or in the mouth
  52. sudden shortness of breath or troubled breathing sweating
  53. swelling
  54. swelling of the face, fingers, or lower legs
  55. swollen glands
  56. swollen joints
  57. tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
  58. tightness in the chest
  59. troubled breathing
  60. unusual bleeding or bruising
  61. unusual tiredness or weakness
  62. vomiting
  63. weak or absent pulses in the legs
  64. weight gain
  65. wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  1. Abdominal or stomach pain
  2. confusion as to time, place, or person
  3. continuing ringing or buzzing or other unexplained noise in the ears
  4. decreased vision
  5. diarrhea
  6. ejaculation without semen
  7. hearing loss
  8. holding false beliefs that cannot be changed by fact
  9. mood or mental changes
  10. seeing, hearing, or feeling things that are not there
  11. stuffy nose
  12. unusual excitement, nervousness, or restlessness
  13. watery eyes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.