Proper Use

Drug information provided by: Micromedex

Make certain your health care professional knows if you are on a low-sodium, low-sugar, or any other special diet. This medicine contains a large amount of sodium (more than 750 mg for each 325 mg of acetaminophen).

Unless otherwise directed by your doctor, do not take more of this medicine than is recommended on the package label. If too much is taken, liver damage or other serious side effects may occur.

To use this medicine:

  • This medicine must be taken in the form of a liquid that is made from the effervescent granules. Do not swallow the granules themselves.
  • To make the liquid, pour the amount of effervescent granules directed on the package into a glass. Then add ½ glass (4 ounces) of cool water.
  • Drink all of the liquid. You may drink the liquid while it is still fizzing or after the fizzing stops.
  • Add a little more water to the glass and drink that, to make sure that you get the full amount of the medicine.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (effervescent granules):
    • For pain and upset stomach:
      • Adults and teenagers—325 to 650 milligrams (mg) of acetaminophen, dissolved in water, every four hours as needed. The bottle cap can be used to measure the dose. There are 325 mg of acetaminophen in three-fourths of a capful.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.