Below are current clinical trials.5 studies in Uterine fibroids
(open studies only).
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The purpose of this study is to investigate the value of ultrasound imaging of microscopic blood vessels as a new biomarker for identifying the difference between benign and cancerous uterine pathologies, and to compare ultrasound imaging to the diagnostics of MRI and (if available), surgical pathology.
Rochester, Minn., La Crosse, Wis., Eau Claire, Wis., Mankato, Minn.
The overall goal of this project is to better enable patients with uterine fibroids (UF) to make informed decisions about treatment options by leveraging the highest possible evidence of healthcare quality. The foundation of this project will be a multi-site, prospective registry of a diverse group of women who have undergone either medical or surgical treatment for UF.
Specifically, the investigators are interested in: comparing management options for symptom relief, preserving reproductive function and comparing effectiveness among different subpopulations, including consideration of patient needs and preferences of treatment options.
The aim is the characterization of the microbiome of subjects experiencing benign reproductive tract disorders and its comparison to the microbiome present in individuals lacking that disorder.
The purpose of this study is to learn how uterine fibroids may be connected to heart disease and high blood pressure. It is not known what causes fibroids, but they frequently occur in women who also have high blood pressure, heart disease, and stroke. The investigators of this study want to learn if certain changes in the blood vessels or nerve activity can put women at risk for these diseases and for fibroids.
This study is being done to support a device labeling change that will allow women who have uterine fibroids and still wish to become pregnant greater access to the ExAblate treatment. In order for the Sponsor to receive permission to change the labeling, data regarding known pregnancies and their outcome are being gathered to show the known safety hazards to women who might wish to get pregnant after an ExAblate treatment
July 06, 2016
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- Segars JH, et al. Proceedings from the third National Institutes of Health International Congress on advances in uterine leiomyoma research: Comprehensive review, conference summary and future recommendations. Human Reproduction Update. 2014;20:309.
- Stewart EA. Epidemiology, clinical manifestations, diagnosis, and natural history of uterine leiomyomas (fibroids). http://www.uptodate.com/home. Accessed May 11, 2016.
- Stewart EA. Uterine fibroids. New England Journal of Medicine. 2015;372:1646.
- Cunningham FG, et al. Pelvic mass. In: Williams Obstetrics. 24th ed. New York, N.Y.: The McGraw-Hill Companies; 2014. http://www.accessmedicine.com. Accessed May 11, 2016.
- Papadakis MA, et al., eds. Gynecologic disorders. In: Current Medical Diagnosis & Treatment 2016. 55th ed. New York, N.Y.: The McGraw-Hill Companies; 2016 http://www.accessmedicine.com. Accessed May 11, 2016.
- Stewart EA. Overview of treatment of uterine leiomyomas (fibroids). http://www.uptodate.com/home. Accessed May 11, 2016.
- Uterine fibroids. Natural Medicines. https://naturalmedicines.therapeuticresearch.com/. Accessed May 15, 2016.
- Liu JP, et al. Herbal preparations for uterine fibroids. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005292.pub3/abstract. Accessed May 11, 2016.
- Cook AJ. AllScripts EPSi. Mayo Clinic, Rochester, Minn. March 25, 2016.
- Stewart EA (expert opinion). Mayo Clinic, Rochester, Minn. June 13, 2016.
- Jefferies A, et al. Modern management of uterine fibroids. Obstetrics, Gynaecology and Reproductive Medicine. 2016;26:127.
- Updated laparoscopic uterine power morcellation in hysterectomy and myomectomy: FDA safety communication. Food and Drug Administration. http://www.fda.gov/medicaldevices/safety/alertsandnotices/ucm424443.htm. Accessed June 19, 2016.