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Below are current clinical trials.
Filter this list of studies by location, status and more.
The purpose of the study is to:
The purpose of this study is to assess the effectiveness and safety of vedolizumab intravenous (IV) in patients who have a proctocolectomy and ileal pouch anal anastomosis for ulcerative colitis, and have developed chronic or recurrent pouchitis, or require continuous antibiotic treatment.
The focus of this study is to retrospectively examine the patterns of use of biological agents and risk factors for discontinuation of these agents in pediatric Crohn’s disease (CD) and ulcerative colitis (UC) within the ICN network. This will be a retrospective longitudinal observational cohort study. The study population for the first portion of the study (Aim 1a below) will be all CD and UC patients in ICN who were diagnosed with IBD prior to age 18. This population will be queried for biologic use prior to age 18. The study population for the remainder of the study will be all CD and UC patients in ICN who received their first biologic medication before 18 years of age and who initiated therapy with the first biologic medication after registration in ICN.
This phase III, double blind, placebo-controlled, multicenter study will investigate the efficacy and safety of etrolizumab during induction and maintenance of remission in participants with moderately to severely active ulcerative colitis (UC) who are refractory to or intolerant of TNF inhibitors.
The purpose of this study is to assess the long-term safety of vedolizumab versus other biologic agents in participants with Ulcerative Colitis or Crohn's Disease.
To evaluate safety and efficacy of two dosing regimens in achieving clinical remission at Week 8 in subjects with moderately to severely active Ulcerative Colitis.
The purpose of this study is to evaluate the effectiveness and safety of vedolizumab intravenous (IV) treatment compared to adalimumab subcutaneous (SC) treatment for patients who have ulcerative colitis.
To assess clinical response to MMX mesalamine/mesalazine between a low and high dose in children and adolescents aged 5-17 years with mild to moderate Ulcerative Colitis (UC) or who are in remission.
The purpose of this study is to determine whether RPC1063 is effective in the treatment of Ulcerative Colitis (UC).
The purpose of this study is to demonstrate the effectiveness and safety of adalimumab administered subcutaneously in pediatric patients with moderate to severe ulcerative colitis.
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