Below are current clinical trials.14 studies in Type 2 diabetes
(open studies only).
Filter this list of studies by location, status and more.
The purpose of this study is to test the hypothesis that patients with T2DM will have greater deterioration in BMSi and in cortical porosity over 3 yrs as compared to sex- and age-matched non-diabetic controls; and identify the circulating hormonal (e.g., estradiol [E2], testosterone [T]) and biochemical (e.g., bone turnover markers, AGEs) determinants of changes in these key parameters of bone quality, and evaluate the possible relationship between existing diabetic complications and skeletal deterioration over time in the T2DM patients.
The purpose of this study is to assess key characteristics of bone quality, specifically material strength and porosity, in patients who have type 2 diabetes. These patients are at an unexplained increased risk for fractures and there is an urgent need to refine clinical assessment for this risk.
The purpose of this study is to estimate the risk of diabetes related complications after total pancreatectomy. We will contact long term survivors after total pancreatectomy to obtain data regarding diabetes related end organ complications.
Adults who gain most of their excess weight in abdominal area or have Type 2 (adult onset) Diabetes typically do not process sugar (glucose) normally in their muscle in response to insulin, especially compared to lean adults or those who have gained most of their excess body fat in their hip and thigh areas. We know that some of this is due to differences in how fat cells release fat molecules into the bloodstream, which in turn affects muscle metabolism. We don’t know whether fat molecules in the bloodstream are handled differently by those with abdominal fat gain, type 2 diabetes or hip and thigh fat gain compared with lean adults. By measuring how muscle handles fat molecules in the bloodstream and how that relates to the ability of insulin to help the muscle use glucose, we will help understand the interaction between fat cells and muscle as it relates to diabetes-related diseases.
Aug. 23, 2017
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- McKulloch DK. Initial management of blood glucose in adults with type 2 diabetes mellitus. http://www.uptodate.com/home. Accessed Nov. 9, 2015.
- Hyperglycemia (High blood glucose). American Diabetes Association. http://www.diabetes.org/living-with-diabetes/treatment-and-care/blood-glucose-control/hyperglycemia.html. Accessed Nov. 9, 2015.
- DKA (ketoacidosis) and ketones. American Diabetes Association. http://www.diabetes.org/living-with-diabetes/complications/ketoacidosis-dka.html. Accessed Nov. 9, 2015.
- Natural medicines in the clinical management of diabetes. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Nov. 9, 2015.
- Diagnosing diabetes and learning about prediabetes. American Diabetes Association. http://www.diabetes.org/diabetes-basics/diagnosis. Accessed Nov. 10, 2015.
- Castro MR (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 1, 2015.