Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, is a chronic condition in which the pancreas produces little or no insulin, a hormone needed to allow sugar (glucose) to enter cells to produce energy. The far more common type 2 diabetes occurs when the body becomes resistant to the effects of insulin or doesn't make enough insulin.
Various factors may contribute to type 1 diabetes, including genetics and exposure to certain viruses. Although type 1 diabetes typically appears during childhood or adolescence, it also can develop in adults.
Despite active research, type 1 diabetes has no cure, although it can be managed. With proper treatment, people who have type 1 diabetes can expect to live longer, healthier lives than they did in the past.
Jan. 23, 2013
- Diabetes mellitus (DM). The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec12/ch158/ch158b.html#sec12-ch158-ch158b-1105. Accessed Sept. 30, 2012.
- Standards of medical care in diabetes — 2013. Diabetes Care. 2013:36:S1.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Sept. 23, 2012.
- Your guide to diabetes: Type 1 and type 2. National Institute of Diabetes and Digestive and Kidney Diseases. http://diabetes.niddk.nih.gov/dm/pubs/type1and2/index.htm. Accessed Sept. 23, 2012.
- What people with diabetes need to know about osteoporosis. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Bone/Osteoporosis/Conditions_Behaviors/diabetes.asp. Accessed Sept. 30, 2012.
- Bainbridge KE. Diabetes and hearing impairment in the United States: Audiometric evidence from the National Health and Nutrition Examination Survey, 1999 to 2004. Annals of Internal Medicine. 2008;149:1.
- Before pregnancy. American Diabetes Association. http://www.diabetes.org/living-with-diabetes/complications/pregnant-women/before-pregnancy.html. Accessed Sept. 30, 2012.
- A1C. American Diabetes Association. http://www.diabetes.org/living-with-diabetes/treatment-and-care/blood-glucose-control/a1c/?keymatch=a1c. Accessed Oct. 1, 2012.
- Bergenstal RM, et al. Effectiveness of sensor-augmented insulin pump therapy in type 1 diabetes. New England Journal of Medicine. 2010;363:311.
- Stem cell information. National Institutes of Health. http://stemcells.nih.gov/info/scireport/chapter7.asp. Accessed Feb. 24, 2011.
- Elleri D, et al. Closed-loop insulin delivery for treatment of type 1 diabetes. BMC Medicine. http://www.biomedcentral.com/1741-7015/9/120. Accessed Oct. 1, 2012.
- Take charge of your diabetes. Centers for Disease Control and Prevention. http://www.cdc.gov/diabetes/pubs/tcyd/vaccin.htm. Accessed Sept. 30, 2012.