Treatments and drugs

By Mayo Clinic Staff

Infants with truncus arteriosus must have surgery. Multiple procedures or surgeries may be necessary, especially as your child grows. Medications may be given before surgery to help improve the health of the heart.


Medications that may be prescribed before surgery may include:

  • Diuretics. Often called water pills, diuretics increase the frequency and volume of urination, preventing fluid from collecting in the body, which is a common effect of heart failure.
  • Ionotropic agents. This type of medication strengthens the heart's contractions.

Surgical procedures

Most infants with truncus arteriosus have surgery within the first few weeks after being born. The exact procedure will depend on your baby's condition. Most commonly your baby's surgeon will:

  • Close the hole between the two ventricles with a patch
  • Separate the upper portion of the pulmonary artery from the single large vessel
  • Implant a tube (conduit) and valve to connect the right ventricle with the upper portion of the pulmonary artery — creating a new, complete pulmonary artery
  • Reconstruct the single large vessel and aorta to create a new, complete aorta

After corrective surgery, your child will need lifelong follow-up care with a cardiologist to monitor his or her heart health. The cardiologist may recommend that your child limit physical activity, particularly intense competitive sports.

Your child will need to take antibiotics before dental procedures and other surgical procedures to prevent infections.

Because the artificial conduit does not grow with your child, follow-up surgeries to replace the conduit valve are necessary as he or she gets older. Newer surgical procedures use a cardiac catheter inserted into a blood vessel in the leg that is then threaded slowly up to the heart to replace the conduit without the need for traditional heart surgery.

In addition, cardiac catheterization with an inflatable balloon tip can be used to open up an obstructed or narrowed artery, which may delay the need for follow-up surgery.


Women who've had surgery to repair truncus arteriosus in infancy need to be evaluated by a cardiologist with expertise in adult congenital heart defects and an obstetrician specializing in high-risk pregnancies before attempting to become pregnant.

Depending on the level of lung damage that occurred before surgery, pregnancy may or may not be recommended. In addition, some drugs taken for heart problems can be harmful to an unborn baby.

Oct. 01, 2015