Overview

Transverse myelitis is an inflammation of both sides of one section of the spinal cord. This neurological disorder often damages the insulating material covering nerve cell fibers (myelin).

Transverse myelitis interrupts the messages that the spinal cord nerves send throughout the body. This can cause pain, muscle weakness, paralysis, sensory problems, or bladder and bowel dysfunction.

Several factors can cause transverse myelitis, including infections and immune system disorders that attack the body's tissues. It could also be caused by other myelin disorders, such as multiple sclerosis.

Treatment for transverse myelitis includes medications and rehabilitative therapy. Most people with transverse myelitis recover at least partially. Those with severe attacks sometimes are left with major disabilities.

Nov. 12, 2016
References
  1. Transverse myelitis fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/transversemyelitis/detail_transversemyelitis.htm. Accessed Aug. 23, 2016.
  2. Transverse myelitis. The Transverse Myelitis Association. http://myelitis.org/symptoms-conditions/transverse-myelitis/. Accessed Aug. 23, 2016.
  3. Eisen A. Disorders affecting the spinal cord. http://www.uptodate.com/home. Accessed Aug. 23, 2016.
  4. Krishnan C, et al. Transverse myelitis. http://www.uptodate.com/home. Accessed Aug. 23, 2016.
  5. Weinshenker BG (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 28, 2016.
  6. Frohman E, et al. Transverse myelitis. The New England Journal of Medicine. 2010; 363:564.
  7. Wingerchuk  D, et al. Acute disseminated encephalomyelitis, transverse myelitis, and neuromyelitis optica. Continuum. 2013;19(4):944.
  8. Scott T, et al. Evidence-based guideline: Clinical evaluation and treatment of transverse myelitis. Neurology. 2011;77:2128.