Overview

Transposition of the great arteries is a serious but rare heart defect present at birth (congenital), in which the two main arteries leaving the heart are reversed (transposed).

Transposition of the great arteries changes the way blood circulates through the body, leaving a shortage of oxygen in blood flowing from the heart to the rest of the body. Without an adequate supply of oxygen-rich blood, the body can't function properly and your child faces serious complications or death without treatment.

Transposition of the great arteries is usually detected either prenatally or within the first hours to weeks of life.

Corrective surgery soon after birth is the usual treatment for transposition of the great arteries. Having a baby with transposition of the great arteries can be alarming, but with proper treatment, the outlook is promising.

Transposition of the great arteries care at Mayo Clinic

Jan. 12, 2016
References
  1. Facts about transposition of the great arteries. Centers for Disease Control and Prevention. http://www.cdc.gov/ncbddd/heartdefects/tga.html. Accessed Oct. 21, 2015.
  2. Fulton DR, et al. Pathophysiology, clinical manifestations, and diagnosis of D-transposition of the great arteries. http://www.uptodate.com/home. Accessed Oct. 21, 2015.
  3. Fulton DR, et al. Management and outcome of D-transposition of the great arteries. http://www.uptodate.com/home. Accessed Oct. 21, 2015.
  4. Transposition of the great arteries. Merck Manuals Professional Edition. http://www.merckmanuals.com/professional/pediatrics/congenital-cardiovascular-anomalies/transposition-of-the-great-arteries. Accessed Oct. 21, 2015.
  5. Fuster V, et al., eds. Congenital heart disease in children and adolescents. In: Hurst's The Heart. 13th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com. Accessed Oct. 21, 2015.
  6. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Sept. 2, 2015.
  7. Kowalik E, et al. Pregnancy and long-term cardiovascular outcomes in women with congenitally corrected transposition of the arteries. International Journal of Gynaecology and Obstetrics. 2014;125:154.
  8. Villafane J, et al. D-transposition of the great arteries. Journal of the American College of Cardiology. 2014;64:498.