Factors that may increase your risk of toxic hepatitis include:
June 01, 2013
- Taking over-the-counter pain relievers or certain prescription drugs. Taking a medication or over-the-counter pain reliever that carries a risk of liver damage increases your risk of toxic hepatitis. This is especially true if you take multiple medications or take more than the recommended dose of medication.
- Having a liver disease. Having a serious liver disorder such as cirrhosis or fatty liver disease makes you much more susceptible to the effects of toxins.
- Having hepatitis. Having viral hepatitis caused by the hepatitis B or C viruses makes your liver more vulnerable.
- Aging. As you age, your liver breaks down harmful substances more slowly. This means that toxins and their byproducts stay in your body longer.
- Drinking alcohol. Drinking alcohol while taking medications increases the toxic effects of most drugs.
- Being female. Because women seem to metabolize certain toxins more slowly than men do, their livers are exposed to higher blood concentrations of harmful substances for longer periods of time. This increases the risk of toxic hepatitis.
- Having certain genetic mutations. Inheriting certain genetic mutations that affect the production and action of liver enzymes that break down toxins may make you more susceptible to toxic hepatitis.
- Working with industrial toxins. Working with certain industrial chemicals puts you at risk of toxic hepatitis.
- Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed April 8, 2013.
- Shannon MW, et al. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. 4th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-7216-0693-4..50002-5&isbn=978-0-7216-0693-4&uniqId=226391226-4. Accessed April 8, 2013.
- Marx JA, et al. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05472-0..X0001-1--TOP&isbn=978-0-323-05472-0&uniqId=230100505-57. Accessed April 8, 2013.
- Kliegman RM, et al. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed April 8, 2013.